期刊
TRANSPLANTATION
卷 100, 期 8, 页码 1629-1638出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/TP.0000000000001100
关键词
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资金
- Department of Defense [W81XWH-09-1-0212, W81XWH-12-1-0414]
- National Institutes of Health [U54CA143837, U54CA151668]
- CPRIT grant from the State of Texas [RP121071]
- Brown Foundation
- Cullen Trust for Health Care Foundation
- Hearst Foundation
- Ernest Cockrell, Jr. Presidential Distinguished Chair
Transplantation is often the only choicemany patients have when suffering from end-stage organ failure. Although the quality of life improves after transplantation, challenges, such as organ shortages, necessary immunosuppression with associated complications, and chronic graft rejection, limit its wide clinical application. Nanotechnology has emerged in the past 2 decades as a field with the potential to satisfy clinical needs in the area of targeted and sustained drug delivery, noninvasive imaging, and tissue engineering. In this article, we provide an overview of popular nanotechnologies and a summary of the current and potential uses of nanotechnology in cell and organ transplantation.
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