期刊
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
卷 82, 期 -, 页码 143-163出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.trac.2016.05.011
关键词
Mixed-mode; Particle-based stationary phase; Monolithic-based stationary phase; High-performance liquid chromatography; Preparation methods; Chromatographic applications
资金
- National Natural Science Foundation of China [21205027]
- Young Talent of Hebei Province
- Baoding Science and Technology Project [15ZG028]
- Hebei University Science Fund for Distinguished Young Scholars [2015JQ06]
Chromatographic stationary phase is the core of high-performance liquid chromatography (HPLC) system. There into, the development of novel stationary phases with high separation efficiency and excellent selectivity has always been the focus of the study. Mixed-mode stationary phases have been proved to be with the merits of high separation selectivity, remarkably high loading capacity, and high separation efficiency. In this study, the recently reported particle-based mixed-mode stationary phases are summarized, especially for those reported in the recent 5 years. These stationary phases are classified based on the HPLC modes, emphasizing the preparation methods and further applications. Furthermore, the recently reported monolithic-based mixed-mode stationary phases for HPLC are also included. (C) 2016 Elsevier B.V. All rights reserved.
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