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Sezgin Gunes et al.
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G. E. Johnson et al.
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Patricia Murphey et al.
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Quantitative approaches for assessing dose-response relationships in genetic toxicology studies
B. B. Gollapudi et al.
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Declaring the existence of human germ-cell mutagens
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Rate of de novo mutations and the importance of father's age to disease risk
Augustine Kong et al.
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A high-throughput next-generation sequencing-based method for detecting the mutational fingerprint of carcinogens
Ahmad Besaratinia et al.
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Anthony M. Lynch et al.
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Christine L. Lemieux et al.
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Variation in genome-wide mutation rates within and between human families
Donald F. Conrad et al.
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Evaluation of Benzo(a)pyrene-Induced Gene Mutations in Male Germ Cells
Nicole Verhofstad et al.
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Characterisation of Muta™Mouse λgt10-lacZ transgene: evidence for in vivo rearrangements
Philip S. Shwed et al.
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Miniaturized flow cytometric in vitro micronucleus assay represents an efficient tool for comprehensively characterizing genotoxicity dose-response relationships
Steven M. Bryce et al.
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Environmental Exposure of the Mouse Germ Line: DNA Adducts in Spermatozoa and Formation of De Novo Mutations during Spermatogenesis
Ann-Karin Olsen et al.
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Elizabeth Julien et al.
CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION (2009)
Dose-response and operational thresholds/NOAELs for in vitro mutagenic effects from DNA-reactive mutagens, MMS and MNU
Lynn H. Pottenger et al.
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In vivo studies in the mouse to define a threshold for the genotoxicity of EMS and ENU
Elmar Gocke et al.
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DNA repair decline during mouse spermiogenesis results in the accumulation of heritable DNA damage
Francesco Marchetti et al.
DNA REPAIR (2008)
Mechanistic influences for mutation induction curves after exposure to DNA-reactive carcinogens
Shareen H. Doak et al.
CANCER RESEARCH (2007)
Expanded simple tandem repeat (ESTR) mutation induction in the male germline: Lessons learned from lab mice
Christopher M. Somers
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Nucleotide excision repair activity varies among murine spermatogenic cell types
GG Xu et al.
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A novel single molecule analysis of spontaneous and radiation-induced mutation at a mouse tandem repeat locus
CL Yauk et al.
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Nucleotide excision repair in rat male germ cells:: low level of repair in intact cells contrasts with high dual incision activity in vitro
J Jansen et al.
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Proliferation and differentiation of spermatogonial stem cells
DG de Rooij
REPRODUCTION (2001)
DNA repair mechanisms and gametogenesis
WM Baarends et al.
REPRODUCTION (2001)
The origins patterns and implications of human spontaneous mutation
JF Crow
NATURE REVIEWS GENETICS (2000)