4.4 Article

Base-promoted alkylation of P(O)OH compounds with amines via C-N bond cleavage

期刊

TETRAHEDRON LETTERS
卷 57, 期 21, 页码 2222-2226

出版社

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2016.04.009

关键词

Alkylation; Tertiary amines; C-N bond cleavage; P(O)-OH compounds

资金

  1. NSFC [21273067, 21476065]
  2. Program for Changjiang Scholars and Innovative Research Team in University [IRT1238]
  3. Fundamental Research Funds for the Central Universities (Hunan University)

向作者/读者索取更多资源

Together with a base, dibromomethane enables the efficient synthesis of a broad range of functionalized phosphinates, phosphonates, and phosphates from P(O)-OH compounds and commercially available amines via C-N bond cleavage, affording the corresponding products in moderate to good yields. (C) 2016 Elsevier Ltd. All rights reserved.

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