期刊
TETRAHEDRON
卷 72, 期 46, 页码 7306-7310出版社
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tet.2016.02.016
关键词
Biotransformation; Dihalotryptophan; Alkynyltryptophan; Tryptophan synthase
We report, for the first time, the use of tryptophan synthase in the generation of L-dihalotryptophans and L-alkynyltryptophans. These previously unpublished compounds will be useful tools in the generation of probes for chemical biology, in biosynthetic diversification and as convenient building blocks for synthesis. (C) 2016 Published by Elsevier Ltd.
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