4.5 Article

Synthesis of Alkoxymethyl Groups Containing Isoxazoles and Chromones

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SYNTHESIS-STUTTGART
卷 49, 期 5, 页码 1122-1130

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GEORG THIEME VERLAG KG
DOI: 10.1055/s-0036-1588327

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isoxazoles; chromones; electrophile-mediated cyclization; oxocarbenium ion

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An oxocarbenium ion mediated cyclization of (Z)-1,3-diaryl-prop-2-yn-1-one O-methyloximes and 3-arylprop-2-yn-1-(2-methoxyphenyl)-1-ones resulted in regioselective formation of functionalized isoxazoles and chromones, respectively. Alkoxy(aryl) methyl group containing compounds were obtained in good and high yields.

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