期刊
SYNLETT
卷 27, 期 15, 页码 2209-2212出版社
GEORG THIEME VERLAG KG
DOI: 10.1055/s-0035-1562114
关键词
Zn(OTf)(2); solvent-free synthesis; C-H activation; A(3) coupling; propargylamine
资金
- UGC New Delhi, India [41-335 /2012 (SR)]
Zn(OTf)(2)-mediated expeditious and solvent-free synthesis of propargylamines via A(3) coupling of aldehydes, amines, and phenylacetylene has been described. The described protocol proceeds effectively with variety of substituted benzaldehydes, enolizable aldehyde, and formaldehyde. Recyclability of the catalyst, low catalyst loading, and use of inexpensive catalyst are the key features of the present protocol.
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