Treatment of Neuroendocrine Liver Metastases

Neuroendocrine tumors are rare and slow-growing malignancies that commonly metastasize to the liver, resulting in hormonal syndromes and death from liver failure. Surgical consultation and liver debulking are key components in management. Traditional surgical resection guidelines do not apply to these tumors as with other cancers. Surgical resection has shown survival benefit even in the event of an incomplete resection. Ablation may be used as an adjunct to resection or in patients who are not candidates for resection. Asymptomatic patients with high-volume disease do as well with intra-arterial therapy as with surgery.