期刊
STRAHLENTHERAPIE UND ONKOLOGIE
卷 192, 期 11, 页码 815-819出版社
SPRINGER HEIDELBERG
DOI: 10.1007/s00066-016-1008-6
关键词
Radiosurgery; Adaptive fractionated stereotactic radiotherapy; Benign meningioma; Gamma Knife; Patient tracking
资金
- Department of Radiation Oncology, University Medical Center Mannheim
- Elekta AB, Stockholm, Sweden
- Elekta AB
- Zeiss AG
Objective The Gamma Knife Icon (Elekta AB, Stockholm, Sweden) allows frameless stereotactic treatment using a combination of cone beam computer tomography (CBCT), a thermoplastic mask system, and an infrared-based high-definition motion management (HDMM) camera system for patient tracking during treatment. We report on the first patient with meningioma at the left petrous bone treated with adaptive fractionated stereotactic radiotherapy (a-gkFSRT). Methods The first patient treated with Gamma Knife Icon at our institute receivedMR imaging for preplanning before treatment. For each treatment fraction, a daily CBCT was performed to verify the actual scull/tumor position. The system automatically adapted the planned shot positions to the daily position and recalculated the dose distribution (online adaptive planning). During treatment, the HDMM system recorded the intrafractional patient motion. Furthermore, the required times were recorded to define a clinical treatment slot. Results Total treatment time was around 20 min. Patient positioning needed 0.8 min, CBCT positioning plus acquisition 1.65 min, CT data processing and adaptive planning 2.66 min, and treatment 15.6 min. The differences for the five daily CBCTs compared to the reference are for rotation: -0.59 +/- 0.49 degrees/0.18 +/- 0.20 degrees/0.05 +/- 0.36 degrees and for translation: 0.94 +/- 0.52 mm/-0.08 +/- 0.08 mm/-1.13 +/- 0.89 mm. Over all fractions, an intrafractional movement of 0.13 +/- 0.04 mm was observed. Conclusion The Gamma Knife Icon allows combining the accuracy of the stereotactic Gamma Knife system with the flexibility of fractionated treatment with the mask system and CBCT. Furthermore, the Icon system introduces a new online patient tracking system to the clinical routine. The interfractional accuracy of patient positioning was controlled with a thermoplastic mask and CBCT.
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