期刊
CLIMACTERIC
卷 18, 期 6, 页码 859-866出版社
TAYLOR & FRANCIS LTD
DOI: 10.3109/13697137.2015.1083003
关键词
MENOPAUSE; SYMPTOMS; VASOMOTOR SYMPTOMS; SLEEP DISTURBANCES; FATIGUE; COGNITIVE FUNCTIONING
资金
- National Institutes of Health
- Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
- National Center for Complementary and Alternative Medicine (NCCAM)
- Office of Research on Women's Health (ORWH)
- NIA [U01 AG032656, U01AG032659, U01AG032669, U01AG032682, U01AG032699, U01AG032700]
- Indiana Clinical and Translational Sciences Institute from the NIH, National Center for Research Resources, Clinical and Translational Sciences Award [UL1RR02571]
Objective To describe self-reported menopausal symptom priorities and their association with demographics and other symptoms among participants in an intervention trial for vasomotor symptoms (VMS).Methods Cross-sectional study embedded in the MsFLASH 02 trial, a three-by-two factorial design of yoga vs. exercise vs. usual activity and omega-3-fatty acid vs. placebo. At baseline, women (n=354) completed hot flush diaries, a card sort task to prioritize symptoms they would most like to alleviate, and standardized questionnaires.Results The most common symptom priorities were: VMS (n=322), sleep (n=191), concentration (n=140), and fatigue (n=116). In multivariate models, women who chose VMS as their top priority symptom (n=210) reported significantly greater VMS severity (p=0.004) and never smoking (p=0.012), and women who chose sleep as their top priority symptom (n=100) were more educated (p0.001) and had worse sleep quality (p<0.001). ROC curves identified sleep scale scores that were highly predictive of ranking sleep as a top priority symptom.Conclusions Among women entering an intervention trial for VMS and with relatively low prevalence of depression and anxiety, VMS was the priority symptom for treatment. A card sort may be a valid tool for quickly assessing symptom priorities in clinical practice and research.
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