期刊
SMALL
卷 12, 期 26, 页码 3510-3515出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/smll.201600677
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- KAKENHI [26750162, 23700567]
- Grants-in-Aid for Scientific Research [26750162, 23700567] Funding Source: KAKEN
Hollow and non-hollow mesoporous silica nanospheres are synthesized and used for cancer vaccine adjuvants. The hollow structure of mesoporous silica nanospheres significantly promote cellular uptake of a model cancer antigen by macrophage-like cells in vitro, improve anti-cancer immunity, CD4(+) and CD8(+) T cell populations in splenocytes of mice in vivo.
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