A charge transfer based ratiometric fluorescent probe for detection of hydrazine in aqueous medium and living cells

An intramolecular charge transfer (ICT) based fluorescent probe 2 has been designed and synthesized for the ratiometric detection of hydrazine in PC3 cell lines. Further, probe 2 demonstrates the selective naked-eye detection of hydrazine in the presence of representative metal ions in an aqueous environment. Further, to promote the selective, economic and easy detection of hydrazine, the fluorescent test strips of probe 2 have been prepared which can detect hydrazine up to femtogram level. (C) 2015 Elsevier B.V. All rights reserved.