期刊
SENSORS AND ACTUATORS B-CHEMICAL
卷 235, 期 -, 页码 179-187出版社
ELSEVIER SCIENCE SA
DOI: 10.1016/j.snb.2016.05.066
关键词
Carbon nanodots; Nitrogen-doped; Multicolor cellular imaging; Co2+ sensing
资金
- National Natural Science Foundation of China [21475080, 21575084, 21575083, 21306108]
- Natural Science Foundation of Shanxi Province [2015011020, 2015112, 2013011009-5]
- Shanxi Scholarship Council of China
- Shanxi Province Hundred Talents Project
We report a facile and eco-friendly strategy for the fabrication of highly fluorescent nitrogen-doped carbon nanodots (N-CDs) and demonstrate their applications for multicolor cellular imaging and Co2+ sensing in living cells. One-pot hydrothermal method using pigskin as the precursor yields bright green-emitting N-CDs, providing an easy way for the production of N-CDs without a tedious synthetic methodology or the toxic/expensive solvents and starting materials. Doping N heteroatoms benefits the generation of N CDs with stronger fluorescence emission. As -prepared N-CDs exhibit exceptional advantages including high fluorescent quantum yield (24.1%), excellent biocompatibility, low -toxicity, and satisfactory chemical stability. Depending on these superior properties, as-synthesized N-CDs have been successfully used for multicolor cellular imaging. More strikingly, as-synthesized N-CDs generates strong response to Co2+ ions and gives rise to the fluorescence quenching and further application is extended to precise and quantitative detection of Co2+ ions in living cells. (C) 2016 Elsevier B.V. All rights reserved.
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