期刊
SENSORS AND ACTUATORS B-CHEMICAL
卷 233, 期 -, 页码 438-444出版社
ELSEVIER SCIENCE SA
DOI: 10.1016/j.snb.2016.04.118
关键词
PSS-GN-Pt nanocomposites; Peroxidase mimetic; Colorimetric method; Glucose detection
资金
- National Natural Science Foundation of China [21205108]
- Scientific Research Foundation for the Returned Overseas Chinese Scholars (State Education Ministry of China)
- Technology Foundation for Selected Overseas Chinese Scholars (Ministry of Personnel of China)
In this work, we developed a highly sensitive and simple colorimetric method for glucose detection using poly( styrene sulfonate)/Pt-modified graphene nanosheets (PSS-GN-Pt) as peroxidase mimetics. First, in the presence of glucose, H2O2 was generated as the main by-product of glucose oxidase (GOx)-catalyzed reaction. Then, the obtained H2O2 triggered the oxidation of 3,3',5,5'-tetramethylbenzidine (TMB) to generate blue color with the aid of PSS-GN-Pt nanocomposites as peroxidase mimetics. Via this method, as low as 9.28 x 10(-8) M glucose could be detected with a linear range from 2 x 10(-7) M to 1 x 10(-3) M. Besides absorbency measuring, the visual detection of glucose by naked eyes could also be realized very easily through the observable color changing from colorless to blue. In addition, this strategy was further used to determine the concentrations of glucose both in injection and serum samples with satisfying results. This proposed nanosystem holds great potential for diabetes mellitus research and can be easily expanded to the detection of various H2O2-involved analytes. (C) 2016 Elsevier B.V. All rights reserved.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据