相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Outcomes of patients with chronic lymphocytic leukemia after discontinuing ibrutinib
Preetesh Jain et al.
BLOOD (2015)
Regulation of Glutamine Carrier Proteins by RNF5 Determines Breast Cancer Response to ER Stress-Inducing Chemotherapies
Young Joo Jeon et al.
CANCER CELL (2015)
Genetic and Pharmacological Screens Converge in Identifying FLIP, BCL2, and IAP Proteins as Key Regulators of Sensitivity to the TRAIL-Inducing Anticancer Agent ONC201/TIC10
J. E. Allen et al.
CANCER RESEARCH (2015)
Small-Molecule ONC201/TIC10 Targets Chemotherapy-Resistant Colorectal Cancer Stem-like Cells in an Akt/Foxo3a/TRAIL-Dependent Manner
Varun V. Prabhu et al.
CANCER RESEARCH (2015)
Identification of TRAIL-inducing compounds highlights small molecule ONC201/TIC10 as a unique anti-cancer agent that activates the TRAIL pathway
Joshua E. Allen et al.
MOLECULAR CANCER (2015)
Phosphorylation of the translation initiation factor eIF2 alpha at serine 51 determines the cell fate decisions of Akt in response to oxidative stress
K. Rajesh et al.
CELL DEATH & DISEASE (2015)
Endoplasmic Reticulum Stress-Activated Cell Reprogramming in Oncogenesis
Eric Chevet et al.
CANCER DISCOVERY (2015)
Signaling through alternative Integrated Stress Response pathways compensates for GCN2 loss in a mouse model of soft tissue sarcoma
Stacey L. Lehman et al.
SCIENTIFIC REPORTS (2015)
A dual role for the anti-apoptotic Bcl-2 protein in cancer: Mitochondria versus endoplasmic reticulum
Haidar Akl et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2014)
Endoplasmic reticulum stress associated responses in cancer
Wen-An Wang et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2014)
Clinical impact of small TP53 mutated subclones in chronic lymphocytic leukemia
Davide Rossi et al.
BLOOD (2014)
Endoplasmic Reticulum Stress in Malignancy
Hanna J. Clarke et al.
CANCER CELL (2014)
Induction of p53-mediated transcription and apoptosis by exportin-1 (XPO1) inhibition in mantle cell lymphoma
Mariko Yoshimura et al.
CANCER SCIENCE (2014)
Selective BCL-2 Inhibition by ABT-199 Causes On-Target Cell Death in Acute Myeloid Leukemia
Rongqing Pan et al.
CANCER DISCOVERY (2014)
ER stress-induced cell death mechanisms
Renata Sano et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2013)
Prognostic impact and targeting of CRM1 in acute myeloid leukemia
Kensuke Kojima et al.
BLOOD (2013)
Xbp1s-Negative Tumor B Cells and Pre-Plasmablasts Mediate Therapeutic Proteasome Inhibitor Resistance in Multiple Myeloma
Chungyee Leung-Hagesteijn et al.
CANCER CELL (2013)
The eIF2α kinases: their structures and functions
Neysan Donnelly et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2013)
Control of oncogenesis by eIF2α phosphorylation: implications in PTEN and PI3K-Akt signaling and tumor treatment
Antonis E. Koromilas et al.
FUTURE ONCOLOGY (2013)
Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia
Timothy J. Ley et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Tight Coordination of Protein Translation and HSF1 Activation Supports the Anabolic Malignant State
Sandro Santagata et al.
SCIENCE (2013)
Dual Inactivation of Akt and ERK by TIC10 Signals Foxo3a Nuclear Translocation, TRAIL Gene Induction, and Potent Antitumor Effects
Joshua E. Allen et al.
SCIENCE TRANSLATIONAL MEDICINE (2013)
TP53 alterations in acute myeloid leukemia with complex karyotype correlate with specific copy number alterations, monosomal karyotype, and dismal outcome
Frank G. Rueckner et al.
BLOOD (2012)
A novel hierarchical prognostic model of AML solely based on molecular mutations
Vera Grossmann et al.
BLOOD (2012)
mTORC1 serves ER stress-triggered apoptosis via selective activation of the IRE1-JNK pathway
H. Kato et al.
CELL DEATH AND DIFFERENTIATION (2012)
PERK Utilizes Intrinsic Lipid Kinase Activity To Generate Phosphatidic Acid, Mediate Akt Activation, and Promote Adipocyte Differentiation
Ekaterina Bobrovnikova-Marjon et al.
MOLECULAR AND CELLULAR BIOLOGY (2012)
Toll-like receptor activation suppresses ER stress factor CHOP and translation inhibition through activation of elF2B
Connie W. Woo et al.
NATURE CELL BIOLOGY (2012)
mTOR Is Essential for the Proteotoxic Stress Response, HSF1 Activation and Heat Shock Protein Synthesis
Shiuh-Dih Chou et al.
PLOS ONE (2012)
Bidirectional crosstalk between endoplasmic reticulum stress and mTOR signaling
Christian Appenzeller-Herzog et al.
TRENDS IN CELL BIOLOGY (2012)
The cell cycle regulator Cdh1 controls the pool sizes of hematopoietic stem cells and mature lineage progenitors by protecting from genotoxic stress
Jo Ishizawa et al.
CANCER SCIENCE (2011)
Leucine Deprivation Increases Hepatic Insulin Sensitivity via GCN2/mTOR/S6K1 and AMPK Pathways
Fei Xiao et al.
DIABETES (2011)
Protein synthesis in plasma cells is regulated by crosstalk between endoplasmic reticulum stress and mTOR signaling
Meidan Goldfinger et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2011)
Impact of TP53 mutation and 17p deletion in mantle cell lymphoma
A. M. Halldorsdottir et al.
LEUKEMIA (2011)
Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress
Ira Tabas et al.
NATURE CELL BIOLOGY (2011)
Akt Determines Cell Fate Through Inhibition of the PERK-eIF2α Phosphorylation Pathway
Zineb Mounir et al.
SCIENCE SIGNALING (2011)
Refinement of cytogenetic classification in acute myeloid leukemia: determination of prognostic significance of rare recurring chromosomal abnormalities among 5876 younger adult patients treated in the United Kingdom Medical Research Council trials
David Grimwade et al.
BLOOD (2010)
Effect of Long-term Storage in TRIzol on Microarray-Based Gene Expression Profiling
Wencai Ma et al.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION (2010)
Autophagy and the Integrated Stress Response
Guido Kroemer et al.
MOLECULAR CELL (2010)
Effective and selective targeting of leukemia cells using a TORC1/2 kinase inhibitor
Matthew R. Janes et al.
NATURE MEDICINE (2010)
ATF4 is necessary and sufficient for ER stress-induced upregulation of REDD1 expression
Michael L. Whitney et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2009)
The significance of TP53 in lymphoid malignancies: mutation prevalence, regulation, prognostic impact and potential as a therapeutic target
K-John J. Cheung et al.
BRITISH JOURNAL OF HAEMATOLOGY (2009)
IRE1α Kinase Activation Modes Control Alternate Endoribonuclease Outputs to Determine Divergent Cell Fates
Dan Han et al.
CELL (2009)
ATF4, an ER Stress and Hypoxia-Inducible Transcription Factor and its Potential Role in Hypoxia Tolerance and Tumorigenesis
Jiangbin Ye et al.
CURRENT MOLECULAR MEDICINE (2009)
Finding disease-specific coordinated functions by multi-function genes: Insight into the coordination mechanisms in diseases
Wencai Ma et al.
GENOMICS (2009)
ATF4-dependent transcription mediates signaling of amino acid limitation
Michael S. Kilberg et al.
TRENDS IN ENDOCRINOLOGY AND METABOLISM (2009)
Some commonly used caspase substrates and inhibitors lack the specificity required to monitor individual caspase activity
Natasha Ann Pereira et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
CHR-2797: An antiproliferative aminopeptidase inhibitor that leads to amino acid deprivation in human leukemic cells
David Krige et al.
CANCER RESEARCH (2008)
The PERK/eIF2α signaling pathway of Unfolded Protein Response is essential for N-(4-hydroxyphenyl)retinamide (4HPR)-induced cytotoxicity in cancer cells
Wai-Lung Lai et al.
EXPERIMENTAL CELL RESEARCH (2008)
MDR1 and BCRP1 expression in leukemic progenitors correlates with chemotherapy response in acute myeloid leukemia
Maria M. Ho et al.
EXPERIMENTAL HEMATOLOGY (2008)
Hypoxia regulates TSC1/2-mTOR signaling and tumor suppression through REDD1-mediated 14-3-3 shuttling
Maurice Phillip DeYoung et al.
GENES & DEVELOPMENT (2008)
Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation
Andrew Y. Choo et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1
Yasemin Sancak et al.
SCIENCE (2008)
A novel mechanism for the control of translation initiation by amino acids, mediated by phosphorylation of eukaryotic initiation factor 2B
Xuemin Wang et al.
MOLECULAR AND CELLULAR BIOLOGY (2008)
A novel function of eIF2α kinases as inducers of the phosphoinositide-3 kinase signaling pathway
Shirin Kazemi et al.
MOLECULAR BIOLOGY OF THE CELL (2007)
Connecting endoplasmic reticulum stress to autophagy by unfolded protein response and calcium
M. Hoyer-Hansen et al.
CELL DEATH AND DIFFERENTIATION (2007)
Proteasome inhibitors induce a terminal unfolded protein response in multiple myeloma cells
Esther A. Obeng et al.
BLOOD (2006)
PERK and GCN2 contribute to eIF2α phosphorylation and cell cycle arrest after activation of the unfolded protein response pathway
RB Hamanaka et al.
MOLECULAR BIOLOGY OF THE CELL (2005)
MDM2 antagonists induce p53-dependent apoptosis in AML: implications for leukemia therapy
K Kojima et al.
BLOOD (2005)
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
A Subramanian et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Mantle-cell lymphoma genotypes identified with CGH to BAC microarrays define a leukemic subgroup of disease and predict patient outcome
F Rubio-Moscardo et al.
BLOOD (2005)
Anoxic induction of ATF-4 through HIF-1-independent pathways of protein stabilization in human cancer cells
K Ameri et al.
BLOOD (2004)
Reinitiation involving upstream ORFs regulates ATF4 mRNA translation in mammalian cells
KM Vattem et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
CHOP induces death by promoting protein synthesis and oxidation in the stressed endoplasmic reticulum
SJ Marciniak et al.
GENES & DEVELOPMENT (2004)
Regulation of mTOR function in response to hypoxia by REDD1 and the TSC1/TSC2 tumor suppressor complex
J Brugarolas et al.
GENES & DEVELOPMENT (2004)
Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response
PD Lu et al.
JOURNAL OF CELL BIOLOGY (2004)
An integrated stress response regulates amino acid metabolism and resistance to oxidative stress
HP Harding et al.
MOLECULAR CELL (2003)
Tumor suppressor genes in normal and malignant hematopoiesis
U Krug et al.
ONCOGENE (2002)
BCL-2, BCL-XL sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis
EHYA Cheng et al.
MOLECULAR CELL (2001)
ATF4 degradation relies on a phosphorylation-dependent interaction with the SCFβTrCP ubiquitin ligase
I Lassot et al.
MOLECULAR AND CELLULAR BIOLOGY (2001)
Regulated translation initiation controls stress-induced gene expression in mammalian cells
HP Harding et al.
MOLECULAR CELL (2000)