期刊
SCIENCE
卷 352, 期 6282, 页码 235-239出版社
AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/science.aad9416
关键词
-
资金
- NIH [5R01GM110068]
- NSF [DBI-1402120, 9601020, 0413449]
- Deutsche Forschungsgemeinschaft [SFB1052]
- Presidential Fund of the Max Planck Society
- Glenview Capital
- Division Of Behavioral and Cognitive Sci
- Direct For Social, Behav & Economic Scie [0413449] Funding Source: National Science Foundation
- Division Of Behavioral and Cognitive Sci
- Direct For Social, Behav & Economic Scie [9601020] Funding Source: National Science Foundation
Although Neandertal sequences that persist in the genomes of modern humans have been identified in Eurasians, comparable studies in people whose ancestors hybridized with both Neandertals and Denisovans are lacking. We developed an approach to identify DNA inherited from multiple archaic hominin ancestors and applied it to whole-genome sequences from 1523 geographically diverse individuals, including 35 previously unknown Island Melanesian genomes. In aggregate, we recovered 1.34 gigabases and 303 megabases of the Neandertal and Denisovan genome, respectively. We use these maps of archaic sequences to show that Neandertal admixture occurred multiple times in different non-African populations, characterize genomic regions that are significantly depleted of archaic sequences, and identify signatures of adaptive introgression.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据