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Comment on Single-trial spike trains in parietal cortex reveal discrete steps during decision-making

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SCIENCE
卷 351, 期 6280, 页码 -

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AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/science.aad3242

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  1. Howard Hughes Medical Institute Funding Source: Medline
  2. NEI NIH HHS [R01 EY011378] Funding Source: Medline
  3. Wellcome Trust [097803] Funding Source: Medline

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Latimer et al. (Reports, 10 July 2015, p. 184) claim that during perceptual decision formation, parietal neurons undergo one-time, discrete steps in firing rate instead of gradual changes that represent the accumulation of evidence. However, that conclusion rests on unsubstantiated assumptions about the time window of evidence accumulation, and their stepping model cannot explain existing data as effectively as evidence-accumulation models.

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