期刊
SCIENCE
卷 351, 期 6269, 页码 162-165出版社
AMER ASSOC ADVANCEMENT SCIENCE
DOI: 10.1126/science.aad2545
关键词
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资金
- South Tyrolean grant [14]
- Ernst Ludwig Ehrlich Studienwerk
- University of Vienna
- Graduate School Human Development in Landscapes
- Excellence Cluster Inflammation at Interfaces
- European Research Council (ERC) starting grant APGREID
- National Institutes of Health from the National Institute of General Medical Sciences/Center for Systems Biology [R01 GM087221, S10 RR027584, 2P50 GM076547]
The stomach bacterium Helicobacter pylori is one of the most prevalent human pathogens. It has dispersed globally with its human host, resulting in a distinct phylogeographic pattern that can be used to reconstruct both recent and ancient human migrations. The extant European population of H. pylori is known to be a hybrid between Asian and African bacteria, but there exist different hypotheses about when and where the hybridization took place, reflecting the complex demographic history of Europeans. Here, we present a 5300-year-old H. pylori genome from a European Copper Age glacier mummy. The Iceman H. pylori is a nearly pure representative of the bacterial population of Asian origin that existed in Europe before hybridization, suggesting that the African population arrived in Europe within the past few thousand years.
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