4.1 Article

Complex of 1-hexadecyl-4-aza-1-azoniabicyclo[2.2.2]octane bromide with copper dibromide: structure, aggregation, and biological activity

期刊

RUSSIAN CHEMICAL BULLETIN
卷 65, 期 5, 页码 1365-1371

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SPRINGER
DOI: 10.1007/s11172-016-1463-3

关键词

alkylated derivative of 1,4-diazabicyclo[2.2.2]octane; complex; aggregation; adsorption; biological activity

资金

  1. Russian Foundation for Basic Research [15-03-05434_a]

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The aggregation and adsorption properties of a new complex of 1-hexadecyl-4-aza-1-azoniabicyclo[2.2.2]octane bromide with copper dibromide were studied by methods of conductometry, tensiometry, and dynamic light scattering. The critical micelle concentration, size of the aggregates, and adsorption characteristics at the water-air interface were determined. The antimicrobial and antifungal effects were established. The studied properties of the complex were compared with the properties of the ligand and cationic surfactants with a head group of the cyclic and acyclic types. The enhanced aggregation ability of the complex and its improved biological activity were shown.

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