期刊
QUALITY OF LIFE RESEARCH
卷 25, 期 12, 页码 3209-3219出版社
SPRINGER
DOI: 10.1007/s11136-016-1337-z
关键词
CUA; Norms; AQoL; QoL; Multi-attribute utility
类别
资金
- National Health and Medical Research Council Project [1006334]
Objectives (i) to demonstrate a method which ameliorates the problem of self-selection in the estimation of population norms from web-based data and (ii) to use the method to calculate population norms for two multi-attribute utility (MAU) instruments, the AQoL-6D and AQoL-8D, and population norms for the sub-scales from which they are constructed. Methods A web-based survey administered the AQoL-8D MAU instrument (which subsumes the AQoL-6D questionnaire), to members of the public along with the AQoL4D which has extant population norms. Age, gender and the AQoL-4D were used as post-stratification auxiliary variables to construct weights to ameliorate the potential effects of self-selection associated with web-based surveys. The weights were used to estimate unbiased population norms. Standard errors from the weighted samples were calculated using Jackknife estimation. Results For both AQoL-6D and AQoL-8D, physical health dimensions decline significantly with age. In contrast, for the majority of the psycho-social dimensions there is a significant U-shaped profile. The net effect is a shallow U-shaped relationship between age and both the AQoL-6D and AQoL-8D utilities. This contrasts with the almost monotonic decline in the utilities derived from the AQoL4D and SF-6D MAU instruments. Conclusions Post-stratification weights were used to ameliorate potential bias in the derivation of norms from web-based data for the AQoL-6D and AQoL-8D. The methods may be used generally to obtain norms when suitable auxiliary variables are available. The inclusion of an enlarged psycho-social component in the two instruments significantly alters the demographic profile.
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