期刊
PSYCHIATRIC GENETICS
卷 26, 期 3, 页码 109-116出版社
LIPPINCOTT WILLIAMS & WILKINS
DOI: 10.1097/YPG.0000000000000129
关键词
lncRNAs; psychiatric disorders; regulation
资金
- NIH [K01 DA029643, R21 AA021380, R21 AA020319, R21AA023237]
- National Alliance for Research on Schizophrenia and Depression (NARSAD) Award [17616]
- ABMRF/The Foundation for Alcohol Research
Long noncoding RNAs (lncRNAs) are nonprotein coding transcripts longer than 200 nucleotides. Many of these lncRNAs have regulatory functions and have recently emerged as major players in governing fundamental biological processes. Here, we review the definition, distribution, identification, databases, analysis, classification, and functions of lncRNAs. We also discuss the potential roles of lncRNAs in the etiological processes of psychiatric disorders and the implications for clinical diagnosis and treatment. Copyright (C) 2016 Wolters Kluwer Health, Inc. All rights reserved.
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