相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。A Novel Carcinoembryonic Antigen T-Cell Bispecific Antibody (CEA TCB) for the Treatment of Solid Tumors
Marina Bacac et al.
CLINICAL CANCER RESEARCH (2016)
RG7386, a Novel Tetravalent FAP-DR5 Antibody, Effectively Triggers FAP-Dependent, Avidity-Driven DR5 Hyperclustering and Tumor Cell Apoptosis
Peter Brunker et al.
MOLECULAR CANCER THERAPEUTICS (2016)
CEA TCB, A NOVEL T-CELL BISPECIFIC ANTIBODY WITH POTENT IN VITRO AND IN VIVO ANTITUMOUR ACTIVITY AGAINST SOLID TUMOURS
Marina Bacac et al.
EUROPEAN JOURNAL OF CANCER (2015)
Highly reduced binding to high and low affinity mouse Fc gamma receptors by L234A/L235A and N297A Fc mutations engineered into mouse IgG2a
E. Arduin et al.
MOLECULAR IMMUNOLOGY (2015)
Structure of FcγRI in complex with Fc reveals the importance of glycan recognition for high-affinity IgG binding
Jinghua Lu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Structural basis for binding of human IgG1 to its high-affinity human receptor FcγRI
Masato Kiyoshi et al.
NATURE COMMUNICATIONS (2015)
A novel bispecific Fap-Dr5 antibody inducing potent and tumor-specific death receptor 5 (Dr5) activation by fibroblast activation protein (Fap)-dependent crosslinking
Katharina Wartha et al.
CANCER RESEARCH (2014)
An engineered Fc variant of an IgG eliminates all immune effector functions via structural perturbations
Omid Vafa et al.
METHODS (2014)
Hepatocyte clearance and pharmacokinetics of recombinant factor IX glycosylation variants
Eric Blasko et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2013)
Novel tumor-targeted, engineered IL-2 variant (IL-2v)-based immunocytokines for immunotherapy of cancer.
Christian Klein et al.
CANCER RESEARCH (2013)
GA201 (RG7160): A Novel, Humanized, Glycoengineered Anti-EGFR Antibody with Enhanced ADCC and Superior In Vivo Efficacy Compared with Cetuximab
Christian A. Gerdes et al.
CLINICAL CANCER RESEARCH (2013)
Effects of altered FcγR binding on antibody pharmacokinetics in cynomolgus monkeys
Maya K. Leabman et al.
MABS (2013)
Analytical FcRn affinity chromatography for functional characterization of monoclonal antibodies
Tilman Schlothauer et al.
MABS (2013)
Isotype and glycoform selection for antibody therapeutics
Roy Jefferis
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2012)
Fc receptor-targeted therapies for the treatment of inflammation, cancer and beyond
P. Mark Hogarth et al.
NATURE REVIEWS DRUG DISCOVERY (2012)
Modulation of antibody effector function
John R. Desjarlais et al.
EXPERIMENTAL CELL RESEARCH (2011)
Advances in the assessment and control of the effector functions of therapeutic antibodies
Xu-Rong Jiang et al.
NATURE REVIEWS DRUG DISCOVERY (2011)
A Medicinal Chemist's Guide to Molecular Interactions
Caterina Bissantz et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
Therapeutic antibodies for autoimmunity and inflammation
Andrew C. Chan et al.
NATURE REVIEWS IMMUNOLOGY (2010)
Specificity and affinity of human Fcγ receptors and their polymorphic variants for human IgG subclasses
Pierre Bruhns et al.
BLOOD (2009)
Activating and inhibitory Fcγ receptors in immunotherapy: being the actor or being the target
Riad Abes et al.
EXPERT REVIEW OF CLINICAL IMMUNOLOGY (2009)
IgG2m4, an engineered antibody isotype with reduced Fc function
Zhiqiang An et al.
MABS (2009)
Structural characterization of a human Fc fragment engineered for lack of effector functions
Vaheh Oganesyan et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2008)
Modulation of therapeutic antibody effector functions by glycosylation engineering:: Influence of Golgi enzyme localization domain and co-expression of heterologous β1,4-N-acetylglucosaminyltransferase III and Golgi α-mannosidase II
C Ferrara et al.
BIOTECHNOLOGY AND BIOENGINEERING (2006)
The carbohydrate at FcγRIIIa Asn-162 -: an element required for high affinity binding to non-fucosylated IgG glycoforms
C Ferrara et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Fc gamma receptors: Old friends and new family members
F Nimmerjahn et al.
IMMUNITY (2006)
Human antibody - Fc receptor interactions illuminated by crystal structures
JM Woof et al.
NATURE REVIEWS IMMUNOLOGY (2004)
Interaction sites on human IgG-Fc for FcγR:: current models
R Jefferis et al.
IMMUNOLOGY LETTERS (2002)
The structure of a human type III Fcγ receptor in complex with Fc
S Radaev et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
High resolution mapping of the binding site on human IgG1 for FcγRI, FcγRII, FcγRIII, and FcRn and design of IgG1 variants with improved binding to the FcγR
RL Shields et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Modification of the Fc region of a primatized IgG antibody to human CD4 retains its ability to modulate CD4 receptors but does not deplete CD4+ T cells in chimpanzees
R Newman et al.
CLINICAL IMMUNOLOGY (2001)
Structure of the Fc fragment of human IgE bound to its high-affinity receptor FcεRIα
SC Garman et al.
NATURE (2000)
The 3.2-Å crystal structure of the human IgG1 Fc fragment-FcγRIII complex
P Sondermann et al.
NATURE (2000)