期刊
PLASMA PROCESSES AND POLYMERS
卷 13, 期 6, 页码 588-597出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/ppap.201600010
关键词
bacterial inactivation; fungal inactivation; non-thermal plasmas; onychomycosis
资金
- National Science Foundation [IIP 1343994]
- National Science Foundation under SBIR program [03603]
- Department of Energy [DE-SC0008380, DE-SC0012500]
- Office of Fusion Energy Science Plasma Science Center
- U.S. Department of Energy (DOE) [DE-SC0008380, DE-SC0012500] Funding Source: U.S. Department of Energy (DOE)
- Directorate For Engineering
- Div Of Industrial Innovation & Partnersh [1533478] Funding Source: National Science Foundation
We report on the use of three cold atmospheric plasma (CAP) devices in treating model nails that have been coated on the backside of the nail with either Escherichia coli (E. coli) bacteria or Trichophyton rubrum (T. rubrum) fungus. We tested a helium plasma jet; a surface microdischarge plasma device; and a floating electrode dielectric barrier discharge. All of the devices, acting through the model nail, showed significant log reductions of bacterial and fungal targets in several tens of minutes. CAP technology appears to offer promise as a safe, effective, and inexpensive therapy for fungal nail infection treatment.
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