期刊
PHYSIOLOGY
卷 31, 期 5, 页码 316-326出版社
AMER PHYSIOLOGICAL SOC
DOI: 10.1152/physiol.00006.2016
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资金
- National Institute of Diabetes and Digestive and Kidney Diseases [P01 DK-41315, R01 DK-57236]
- 24th General Assembly of the Japanese Association of Medical Sciences
- [R01 DK-091336]
Interstitial cells of mesenchymal origin form gap junctions with smooth muscle cells in visceral smooth muscles and provide important regulatory functions. In gastrointestinal (GI) muscles, there are two distinct classes of interstitial cells, c-Kit(+) interstitial cells of Cajal and PDGFR alpha(+) cells, that regulate motility patterns. Loss of these cells may contribute to symptoms in GI motility disorders.
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