期刊
PHYSICAL CHEMISTRY CHEMICAL PHYSICS
卷 18, 期 18, 页码 12576-12581出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c6cp01586g
关键词
-
资金
- World Premier International Research Center Initiative (WPI Initiative), MEXT, Japan
- Core Research for Evolutional Science and Technology (CREST) program of Japan Science and Technology Agency (JST), Japan
- JSPS KAKENHI [26790003, 26104541, 24104005, 15K12136]
- Grants-in-Aid for Scientific Research [15K17890, 26104541, 15K12136, 26880002, 15H01715, 26790003, 24104005] Funding Source: KAKEN
In this study, a Langmuir-Blodgett (LB) system has been utilized for the regulation of polymerization of a DNA origami structure at the air-water interface as a two-dimensionally confined medium, which enables dynamic condensation of DNA origami units through variation of the film area at the macroscopic level (ca. 10-100 cm(2)). DNA origami sheets were conjugated with a cationic lipid (dioctadecyldimethylammonium bromide, 2C(18)N(+)) by electrostatic interaction and the corresponding LB-film was prepared. By applying dynamic pressure variation through compression-expansion processes, the lipid-modified DNA origami sheets underwent anisotropic polymerization forming a one-dimensionally assembled belt-shaped structure of a high aspect ratio although the thickness of the polymerized DNA origami was maintained at the unimolecular level. This approach opens up a new field of mechanical induction of the self-assembly of DNA origami structures.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据