Network and Multilayer Network Approaches to Understanding Human Brain Dynamics

Network neuroscience provides a systems approach to the study of the brain and enables the examination of interactions measured at different temporal and spatial scales. We review current methods to quantify the structure of brain networks and compare that structure across different clinical cohorts, cognitive states, and subjects. We further introduce the emerging mathematical concept of multilayer networks and describe the advantages of this approach to model changing brain dynamics over time. We conclude by offering several concrete examples of how multilayer network approaches to neuroimaging data provide novel insights into brain structure and evolving function.