期刊
PHARMACOLOGICAL RESEARCH
卷 112, 期 -, 页码 84-98出版社
ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
DOI: 10.1016/j.phrs.2016.01.027
关键词
Neutrophil; Phagocytosis; Neutrophil extracellular traps; Arthritis; Neutrophil recruitment; Infection; Tissue damage
The inflammatory response in the joint can induce an intense accumulation of leukocytes in the tissue that frequently results in severe local damage and loss of function. Neutrophils are essential cells to combat many pathogens, but their arsenal can contribute or aggravate articular inflammation. Here we summarized some aspects of neutrophil biology, their role in inflammation and indicated how the modulation of neutrophil functions could be useful for the treatment of different forms of arthritis. (C) 2016 Elsevier Ltd. All rights reserved.
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