期刊
PEDIATRIC BLOOD & CANCER
卷 64, 期 2, 页码 284-286出版社
WILEY
DOI: 10.1002/pbc.26224
关键词
chronic pain; kaposiform hemangioendothelioma; sirolimus
Kaposiform hemangioendothelioma (KHE) is a rare aggressive vascular tumor of skin and deep soft tissues that typically presents in infancy and may be associated with a potentially life-threatening coagulopathy known as Kasabach-Merrit phenomenon (KMP). Recent advances in medical therapy have successfully treated many patients. However, our knowledge regarding the natural history of these lesions and optimum surveillance strategies remains rudimentary. We report two young women who had KHE with KMP treated in infancy and presented in adolescence with comorbidities related to their KHE tumor. This presentation supports the need for long-term surveillance in these patients.
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