相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Elevated tissue Cr levels, increased plasma oxidative markers, and global hypomethylation of blood DNA in male Sprague-Dawley rats exposed to potassium dichromate in drinking water
Yu Wang et al.
ENVIRONMENTAL TOXICOLOGY (2016)
Biomolecular bases of the senescence process and cancer. A new approach to oncological treatment linked to ageing
Iker Badiola et al.
AGEING RESEARCH REVIEWS (2015)
Genetic factors associated with longevity: A review of recent findings
Aladdin H. Shadyab et al.
AGEING RESEARCH REVIEWS (2015)
Cellular senescence-like features of lung fibroblasts derived from idiopathic pulmonary fibrosis patients
Hagai Yanai et al.
AGING-US (2015)
Redox Regulation of NLRP3 Inflammasomes: ROS as Trigger or Effector?
Justine M. Abais et al.
ANTIOXIDANTS & REDOX SIGNALING (2015)
The Interplay Between Respiratory Supercomplexes and ROS in Aging
Maria Luisa Genova et al.
ANTIOXIDANTS & REDOX SIGNALING (2015)
SOD3 Variant, R213G, Altered SOD3 Function, Leading to ROS-Mediated Inflammation and Damage in Multiple Organs of Premature Aging Mice
Myung-Ja Kwon et al.
ANTIOXIDANTS & REDOX SIGNALING (2015)
The paradoxical role of thioredoxin on oxidative stress and aging
Geneva M. Cunningham et al.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2015)
ROS and energy metabolism in cancer cells: alliance for fast growth
Sang Won Kang et al.
ARCHIVES OF PHARMACAL RESEARCH (2015)
Mitochondria: Are they causal players in cellular senescence?
Clara Correia-Melo et al.
BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS (2015)
Nrf2 regulates ROS production by mitochondria and NADPH oxidase
Stjepana Kovac et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2015)
Mitochondria in health, aging and diseases: the epigenetic perspective
Patrizia D'Aquila et al.
BIOGERONTOLOGY (2015)
Mitochondrial responsibility in ageing process: innocent, suspect or guilty
Guillermo Lopez-Lluch et al.
BIOGERONTOLOGY (2015)
A ratiometric fluorescent probe based on a coumarin-hemicyanine scaffold for sensitive and selective detection of endogenous peroxynitrite
Xin Zhou et al.
BIOSENSORS & BIOELECTRONICS (2015)
From cell senescence to age-related diseases: differential mechanisms of action of senescence-associated secretory phenotypes
Hae-Ok Byun et al.
BMB REPORTS (2015)
Promoting Health and Longevity through Diet: From Model Organisms to Humans
Luigi Fontana et al.
CELL (2015)
Phagocyte NADPH oxidase and specific immunity
Julien Cachat et al.
CLINICAL SCIENCE (2015)
ROS-Mediated DNA Methylation Pattern Alterations in Carcinogenesis
Qihan Wu et al.
CURRENT DRUG TARGETS (2015)
Mechanisms of activation of the transcription factor Nrf2 by redox stressors, nutrient cues, and energy status and the pathways through which it attenuates degenerative disease
Lauren E. Tebay et al.
FREE RADICAL BIOLOGY AND MEDICINE (2015)
Protective action of green tea catechins in neuronal mitochondria during aging
Marco Assuncao et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2015)
Immune mechanisms linked to depression via oxidative stress and neuroprogression
Nataliia Bakunina et al.
IMMUNOLOGY (2015)
Regulation of Hypoxia-Inducible Factor-1a by Reactive Oxygen Species : New Developments in an Old Debate
Shahrzad Movafagh et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2015)
A mitochondrial superoxide theory for oxidative stress diseases and aging
Hiroko P. Indo et al.
JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION (2015)
Telomere length and telomerase activity in non-small cell lung cancer prognosis: clinical usefulness of a specific telomere status
Tamara Fernandez-Marcelo et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2015)
Mitochondrial dynamics: Orchestrating the journey to advanced age
Agnieszka K. Biala et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2015)
Noncoding RNA in age-related cardiovascular diseases
Simona Greco et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2015)
The mitochondrial lncRNA ASncmtRNA-2 is induced in aging and replicative senescence in Endothelial Cells
Valentina Bianchessi et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2015)
Metabolic Regulation of the Ultradian Oscillator Hes1 by Reactive Oxygen Species
Simone Ventre et al.
JOURNAL OF MOLECULAR BIOLOGY (2015)
NADPH oxidases, Nox: new isoenzymes family
Minh Vu Chuong Nguyen et al.
M S-MEDECINE SCIENCES (2015)
Reconfiguration of DNA methylation in aging
Michele Zampieri et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2015)
Cysteine-mediated redox signalling in the mitochondria
D. W. Bak et al.
MOLECULAR BIOSYSTEMS (2015)
The Histone Demethylase Jumonji Coordinates Cellular Senescence Including Secretion of Neural Stem Cell-Attracting Cytokines
Patrick M. Perrigue et al.
MOLECULAR CANCER RESEARCH (2015)
MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation
Remi-Martin Laberge et al.
NATURE CELL BIOLOGY (2015)
Role of Oxidative RNA Damage in Chronic-Degenerative Diseases
Carmela Fimognari
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2015)
Cellular Mechanisms of Oxidative Stress and Action in Melanoma
Mario Venza et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2015)
Telomere Dysfunction and Cell Senescence in Chronic Lung Diseases: Therapeutic Potential
Serge Adnot et al.
PHARMACOLOGY & THERAPEUTICS (2015)
Epigenomes as therapeutic targets
Christopher A. Hamm et al.
PHARMACOLOGY & THERAPEUTICS (2015)
Chronic Hepatitis B Virus Infection: The Relation between Hepatitis B Antigen Expression, Telomere Length, Senescence, Inflammation and Fibrosis
Phaedra M. Tachtatzis et al.
PLOS ONE (2015)
Therapeutic targeting of replicative immortality
Paul Yaswen et al.
SEMINARS IN CANCER BIOLOGY (2015)
Radical Oxygen Species, Exercise and Aging: An Update
Mohamed Amine Bouzid et al.
SPORTS MEDICINE (2015)
A novel role of long non-coding RNAs in response to X-ray irradiation
Jihua Nie et al.
TOXICOLOGY IN VITRO (2015)
Protecting the mitochondrial powerhouse
Morten Scheibye-Knudsen et al.
TRENDS IN CELL BIOLOGY (2015)
Nongenetic inheritance and transgenerational epigenetics
Moshe Szyf
TRENDS IN MOLECULAR MEDICINE (2015)
The role of the microbiota in ageing: current state and perspectives
Denise B. Lynch et al.
WILEY INTERDISCIPLINARY REVIEWS-SYSTEMS BIOLOGY AND MEDICINE (2015)
Metabolic Syndrome, Aging and Involvement of Oxidative Stress
Francesca Bonomini et al.
AGING AND DISEASE (2015)
Editorial: the changing faces of glutathione, a cellular protagonist
Alfonso Pompella et al.
FRONTIERS IN PHARMACOLOGY (2015)
Redox regulation of FoxO transcription factors
Lars-Oliver Klotz et al.
REDOX BIOLOGY (2015)
Mitochondrial effectors of cellular senescence: beyond the free radical theory of aging
Dorian V. Ziegler et al.
AGING CELL (2015)
Oxidative stress and autophagy: the clash between damage and metabolic needs
G. Filomeni et al.
CELL DEATH AND DIFFERENTIATION (2015)
The controversial role of the Polycomb group proteins in transcription and cancer: how much do we not understand Polycomb proteins?
Andrea Scelfo et al.
FEBS JOURNAL (2015)
Redox Regulation of Inflammation: Old Elements, a New Story
Yunlong Lei et al.
MEDICINAL RESEARCH REVIEWS (2015)
Overexpression of the Novel Senescence Marker β-Galactosidase (GLB1) in Prostate Cancer Predicts Reduced PSA Recurrence
Jennifer Wagner et al.
PLOS ONE (2015)
Visualization of Endogenous and Exogenous Hydrogen Peroxide Using A Lysosome-Targetable Fluorescent Probe
Dabin Kim et al.
SCIENTIFIC REPORTS (2015)
Free Radicals: Properties, Sources, Targets, and Their Implication in Various Diseases
Alugoju Phaniendra et al.
INDIAN JOURNAL OF CLINICAL BIOCHEMISTRY (2015)
Oxidative Stress in Aging Human Skin
Mark Rinnerthaler et al.
BIOMOLECULES (2015)
The mitochondrial genome in aging and senescence
Andrea Lauri et al.
AGEING RESEARCH REVIEWS (2014)
Molecular Characterization of Reactive Oxygen Species in Systemic and Pulmonary Hypertension
Li Zuo et al.
AMERICAN JOURNAL OF HYPERTENSION (2014)
Visualization of Phagosomal Hydrogen Peroxide Production by a Novel Fluorescent Probe That Is Localized via SNAP-tag Labeling
Masahiro Abo et al.
ANALYTICAL CHEMISTRY (2014)
Nox Enzymes and New Thinking on Reactive Oxygen: A Double-Edged Sword Revisited
J. David Lambeth et al.
ANNUAL REVIEW OF PATHOLOGY: MECHANISMS OF DISEASE, VOL 9 (2014)
Stem Cells, Redox Signaling, and Stem Cell Aging
Raymond Liang et al.
ANTIOXIDANTS & REDOX SIGNALING (2014)
Roles of DUOX-Mediated Hydrogen Peroxide in Metabolism, Host Defense, and Signaling
Xavier De Deken et al.
ANTIOXIDANTS & REDOX SIGNALING (2014)
Free Radicals in Cross Talk Between Autophagy and Apoptosis
Vitaliy O. Kaminskyy et al.
ANTIOXIDANTS & REDOX SIGNALING (2014)
Mitochondria as a Target in the Therapeutic Properties of Curcumin
Joyce Trujillo et al.
ARCHIV DER PHARMAZIE (2014)
Regulation of the human thioredoxin gene promoter and its key substrates: A study of functional and putative regulatory elements
Hye-Jin Kim Hawkes et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2014)
Detection and interpretation of 8-oxodG and 8-oxoGua in urine, plasma and cerebrospinal fluid
Henrik E. Poulsen et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS (2014)
How do I kill thee? Let me count the ways: p53 regulates PARP-1 dependent necrosis
Rana Elkholi et al.
BIOESSAYS (2014)
8-Hydroxy-2′-Deoxyguanosine and Cardiovascular Disease: a Systematic Review
Lona J. Kroese et al.
CURRENT ATHEROSCLEROSIS REPORTS (2014)
ROS Function in Redox Signaling and Oxidative Stress
Michael Schieber et al.
CURRENT BIOLOGY (2014)
Mitochondria, Energetics, Epigenetics, and Cellular Responses to Stress
Daniel T. Shaughnessy et al.
ENVIRONMENTAL HEALTH PERSPECTIVES (2014)
Mitochondria in ageing: there is metabolism beyond the ROS
Michael Breitenbach et al.
FEMS YEAST RESEARCH (2014)
Revisiting an age-old question regarding oxidative stress
Yael H. Edrey et al.
FREE RADICAL BIOLOGY AND MEDICINE (2014)
Tumour Suppressors and Cellular Senescence
Adelyne S. L. Chan et al.
IUBMB LIFE (2014)
Screening of microRNAs associated with Alzheimer's disease using oxidative stress cell model and different strains of senescence accelerated mice
Rui Zhang et al.
JOURNAL OF THE NEUROLOGICAL SCIENCES (2014)
Epigenetic modifications and NF-κB pathway activity in Cu,Zn-SOD-deficient mice
Agnieszka Siomek et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2014)
PROTEIN CARBONYLATION: PROTEOMICS, SPECIFICITY AND RELEVANCE TO AGING
Elisa Cabiscol et al.
MASS SPECTROMETRY REVIEWS (2014)
MASS SPECTROMETRY AND REDOX PROTEOMICS: APPLICATIONS IN DISEASE
D. Allan Butterfield et al.
MASS SPECTROMETRY REVIEWS (2014)
The role of senescent cells in ageing
Jan M. van Deursen
NATURE (2014)
The role of iron and reactive oxygen species in cell death
Scott J. Dixon et al.
NATURE CHEMICAL BIOLOGY (2014)
Cellular senescence: from physiology to pathology
Daniel Munoz-Espin et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)
Apoptosis, Fibrosis and Senescence
Didier Portilla
NEPHRON CLINICAL PRACTICE (2014)
NAR Breakthrough Article 7SL RNA represses p53 translation by competing with HuR
Kotb Abdelmohsen et al.
NUCLEIC ACIDS RESEARCH (2014)
Physiological roles of long noncoding RNAs: insight from knockout mice
Lingjie Li et al.
TRENDS IN CELL BIOLOGY (2014)
Characterization of novel markers of senescence and their prognostic potential in cancer
M. Althubiti et al.
CELL DEATH & DISEASE (2014)
Long noncoding RNA PANDA and scaffold-attachment-factor SAFA control senescence entry and exit
Pavan Kumar Puvvula et al.
NATURE COMMUNICATIONS (2014)
Evaluation of methods of detecting cell reactive oxygen species production for drug screening and cell cycle studies
Lampson M. Fan et al.
JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS (2014)
Nitric Oxide, Oxidative Stress, and p66Shc Interplay in Diabetic Endothelial Dysfunction
Alessandra Magenta et al.
BIOMED RESEARCH INTERNATIONAL (2014)
Oxidative Stress, Prooxidants, and Antioxidants: The Interplay
Anu Rahal et al.
BIOMED RESEARCH INTERNATIONAL (2014)
ROS, Notch, and Wnt Signaling Pathways: Crosstalk between Three Major Regulators of Cardiovascular Biology
C. Caliceti et al.
BIOMED RESEARCH INTERNATIONAL (2014)
Positive oxidative stress in aging and aging-related disease tolerance
Liang-Jun Yan
REDOX BIOLOGY (2014)
Antioxidants in health and disease
E. Ginter et al.
BRATISLAVA MEDICAL JOURNAL-BRATISLAVSKE LEKARSKE LISTY (2014)
Genomes of replicatively senescent cells undergo global epigenetic changes leading to gene silencing and activation of transposable elements
Marco Cecco et al.
AGING CELL (2013)
Senescence-associated lncRNAs: senescence-associated long noncoding RNAs
Kotb Abdelmohsen et al.
AGING CELL (2013)
Increased expression of senescence markers in cystic fibrosis airways
Bernard M. Fischer et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2013)
Oxidative Stress Induces Hypomethylation of LINE-1 and Hypermethylation of the RUNX3 Promoter in a Bladder Cancer Cell Line
Wikrom Wongpaiboonwattana et al.
ASIAN PACIFIC JOURNAL OF CANCER PREVENTION (2013)
Do age-related changes in DNA methylation play a role in the development of age-related diseases?
Sanne D. van Otterdijk et al.
BIOCHEMICAL SOCIETY TRANSACTIONS (2013)
miR-9a Minimizes the Phenotypic Impact of Genomic Diversity by Buffering a Transcription Factor
Justin J. Cassidy et al.
CELL (2013)
Co-regulation of senescence-associated genes by oncogenic homeobox proteins and polycomb repressive complexes
Nadine Martin et al.
CELL CYCLE (2013)
Dual CDK4/CDK6 Inhibition Induces Cell-Cycle Arrest and Senescence in Neuroblastoma
JulieAnn Rader et al.
CLINICAL CANCER RESEARCH (2013)
Senescent Cells: A Novel Therapeutic Target for Aging and Age-Related Diseases
R. M. Naylor et al.
CLINICAL PHARMACOLOGY & THERAPEUTICS (2013)
Redox regulation of protein kinases
Thu H. Truong et al.
CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY (2013)
Antioxidant supplements and mortality
Goran Bjelakovic et al.
CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE (2013)
Redox Homeostasis and Epigenetics in Non-alcoholic Fatty Liver Disease (NAFLD)
Christine Podrini et al.
CURRENT PHARMACEUTICAL DESIGN (2013)
MicroRNAs in age-related diseases
Stefanie Dimmeler et al.
EMBO MOLECULAR MEDICINE (2013)
Redox regulation of protein kinases
Aoife Corcoran et al.
FEBS JOURNAL (2013)
Free radical biology for medicine: learning from nonalcoholic fatty liver disease
Gaetano Serviddio et al.
FREE RADICAL BIOLOGY AND MEDICINE (2013)
Redox signaling in cardiovascular health and disease
Nageswara R. Madamanchi et al.
FREE RADICAL BIOLOGY AND MEDICINE (2013)
Long Noncoding RNAs: Past, Present, and Future
Johnny T. Y. Kung et al.
GENETICS (2013)
Oxidative Stress and Epigenetic Regulation in Ageing and Age-Related Diseases
Chiara Cencioni et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2013)
Coming of age: molecular drivers of aging and therapeutic opportunities
Christopher B. Newgard et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
The role of mitochondria in aging
Ana Bratic et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
The role of mitochondrial DNA mutations and free radicals in disease and ageing
M. Lagouge et al.
JOURNAL OF INTERNAL MEDICINE (2013)
Mitochondrial DNA methylation as a next-generation biomarker and diagnostic tool
Vito Iacobazzi et al.
MOLECULAR GENETICS AND METABOLISM (2013)
Senescent cells harbour features of the cancer epigenome
Hazel A. Cruickshanks et al.
NATURE CELL BIOLOGY (2013)
Peroxisome proliferator-activated receptor (PPAR)β/δ, a possible nexus of PPARα- and PPARγ-dependent molecular pathways in neurodegenerative diseases: Review and novel hypotheses
Stepan Aleshin et al.
NEUROCHEMISTRY INTERNATIONAL (2013)
Senescence and aging: the critical roles of p53
A. Rufini et al.
ONCOGENE (2013)
Oxidative Stress in Cardiovascular Diseases and Obesity: Role of p66Shc and Protein Kinase C
Elena De Marchi et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2013)
ROS and Brain Diseases: The Good, the Bad, and the Ugly
Aurel Popa-Wagner et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2013)
Androgen deprivation induces senescence characteristics in prostate cancer cells in vitro and in vivo
Jonathan A. Ewald et al.
PROSTATE (2013)
A ROS rheostat for cell fate regulation
Maria Maryanovich et al.
TRENDS IN CELL BIOLOGY (2013)
Long Noncoding RNA MALAT1 Controls Cell Cycle Progression by Regulating the Expression of Oncogenic Transcription Factor B-MYB
Vidisha Tripathi et al.
PLOS GENETICS (2013)
The pathological roles of environmental and redox stresses in cardiovascular diseases
Sahoko Ichihara
ENVIRONMENTAL HEALTH AND PREVENTIVE MEDICINE (2013)
Histone Modifications in Senescence-Associated Resistance to Apoptosis by Oxidative Stress
Yan Y. Sanders et al.
REDOX BIOLOGY (2013)
Sites of reactive oxygen species generation by mitochondria oxidizing different substrates
Casey L. Quinlan et al.
REDOX BIOLOGY (2013)
Prospective Treatment of Age-Related Diseases by Slowing Down Aging
Mikhail V. Blagosklonny
AMERICAN JOURNAL OF PATHOLOGY (2012)
NADPH Oxidases as Regulators of Tumor Angiogenesis: Current and Emerging Concepts
Sanja Coso et al.
ANTIOXIDANTS & REDOX SIGNALING (2012)
Redox Regulation of p53, Redox Effectors Regulated by p53: A Subtle Balance
Agnes Maillet et al.
ANTIOXIDANTS & REDOX SIGNALING (2012)
Role of peroxisomes in ROS/RNS-metabolism: Implications for human disease
Marc Fransen et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2012)
Hypoxia-derived oxidative stress mediates epigenetic repression of PKCε gene in foetal rat hearts
Andrew J. Patterson et al.
CARDIOVASCULAR RESEARCH (2012)
Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling
Paul D. Ray et al.
CELLULAR SIGNALLING (2012)
Aging and Atherosclerosis Mechanisms, Functional Consequences, and Potential Therapeutics for Cellular Senescence
Julie C. Wang et al.
CIRCULATION RESEARCH (2012)
AMP-activated protein kinase, stress responses and cardiovascular diseases
Shaobin Wang et al.
CLINICAL SCIENCE (2012)
Free radical biology of the cardiovascular system
Alex F. Chen et al.
CLINICAL SCIENCE (2012)
Role of Forkhead Transcription Factors in Diabetes-Induced Oxidative Stress
Bhaskar Ponugoti et al.
EXPERIMENTAL DIABETES RESEARCH (2012)
Tumor suppressor genes and ROS: complex networks of interactions
Beyza Vurusaner et al.
FREE RADICAL BIOLOGY AND MEDICINE (2012)
The influence of reactive oxygen species on cell cycle progression in mammalian cells
Eline Hendrike Verbon et al.
GENE (2012)
Regulation of intracellular signalling through cysteine oxidation by reactive oxygen species
Hiroaki Miki et al.
JOURNAL OF BIOCHEMISTRY (2012)
The emerging role of ROS-generating NADPH oxidase NOX4 in DNA-damage responses
Urbain Weyemi et al.
MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH (2012)
The microRNA miR-34 modulates ageing and neurodegeneration in Drosophila
Nan Liu et al.
NATURE (2012)
Landscape of transcription in human cells
Sarah Djebali et al.
NATURE (2012)
Free radicals and antioxidants: updating a personal view
Barry Halliwell
NUTRITION REVIEWS (2012)
Differential Expression of Senescence and Cell Death Factors in Non-Small Cell Lung and Colorectal Tumors Showing Telomere Attrition
Tamara Fernandez-Marcelo et al.
ONCOLOGY (2012)
Anticancer Activity of Green Tea Polyphenols in Prostate Gland
Pierpaola Davalli et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2012)
A Stochastic Step Model of Replicative Senescence Explains ROS Production Rate in Ageing Cell Populations
Conor Lawless et al.
PLOS ONE (2012)
Astrocyte Senescence as a Component of Alzheimer's Disease
Rekha Bhat et al.
PLOS ONE (2012)
Epigenetic regulation of hypoxic sensing disrupts cardiorespiratory homeostasis
Jayasri Nanduri et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
From Sulfenylation to Sulfhydration: What a Thiolate Needs to Tolerate
Toren Finkel
SCIENCE SIGNALING (2012)
Epigenetic genome-wide association methylation in aging and longevity
Danny Ben-Avraham et al.
EPIGENOMICS (2012)
Redox Mechanisms in Regulation of Adipocyte Differentiation: Beyond a General Stress Response
Guei-Sheung Liu et al.
Cells (2012)
Telomere Length Is a Determinant of Emphysema Susceptibility
Jonathan K. Alder et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2011)
Redox Regulation of Protein Kinases as a Modulator of Vascular Function
Greg A. Knock et al.
ANTIOXIDANTS & REDOX SIGNALING (2011)
Forkhead Homeobox Type O Transcription Factors in the Responses to Oxidative Stress
Peter Storz
ANTIOXIDANTS & REDOX SIGNALING (2011)
Expression of Chr9p21 genes CDKN2B (p15INK4b), CDKN2A (p16INK4a, p14ARF) and MTAP in human atherosclerotic plaque
Lesca Miriam Holdt et al.
ATHEROSCLEROSIS (2011)
hTERT Overexpression Alleviates Intracellular ROS Production, Improves Mitochondrial Function, and Inhibits ROS-Mediated Apoptosis in Cancer Cells
Inthrani R. Indran et al.
CANCER RESEARCH (2011)
miR-200c is upregulated by oxidative stress and induces endothelial cell apoptosis and senescence via ZEB1 inhibition
A. Magenta et al.
CELL DEATH AND DIFFERENTIATION (2011)
Crosstalk of reactive oxygen species and NF-kappa B signaling
Michael J. Morgan et al.
CELL RESEARCH (2011)
Pulmonary Artery Smooth Muscle Cell Senescence Is a Pathogenic Mechanism for Pulmonary Hypertension in Chronic Lung Disease
Hibo Noureddine et al.
CIRCULATION RESEARCH (2011)
p38MAPK is a novel DNA damage response-independent regulator of the senescence-associated secretory phenotype
Adam Freund et al.
EMBO JOURNAL (2011)
Therapeutically activating RB: reestablishing cell cycle control in endocrine therapy-resistant breast cancer
Chellappagounder Thangavel et al.
ENDOCRINE-RELATED CANCER (2011)
Induction of senescence markers after neo-adjuvant chemotherapy of malignant pleural mesothelioma and association with clinical outcome: An exploratory analysis
Roy Sidi et al.
EUROPEAN JOURNAL OF CANCER (2011)
Astrocytes in the aging brain express characteristics of senescence-associated secretory phenotype
Antero Salminen et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2011)
Extending life span by increasing oxidative stress
Michael Ristow et al.
FREE RADICAL BIOLOGY AND MEDICINE (2011)
MicroRNA profiling of Parkinson's disease brains identifies early downregulation of miR-34b/c which modulate mitochondrial function
Elena Minones-Moyano et al.
HUMAN MOLECULAR GENETICS (2011)
Hsa-miR-34b is a plasma-stable microRNA that is elevated in pre-manifest Huntington's disease
Philip Michael Gaughwin et al.
HUMAN MOLECULAR GENETICS (2011)
Reactive Oxygen Species (ROS)-Induced genetic and epigenetic alterations in human carcinogenesis
Dominique Ziech et al.
MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2011)
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
Darren J. Baker et al.
NATURE (2011)
Caveolin-1, cellular senescence and age-related diseases
Huafei Zou et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2011)
Age-associated changes in expression of small, noncoding RNAs, including microRNAs, in C. elegans
Masaomi Kato et al.
RNA (2011)
Protein modification and replicative senescence of WI-38 human embryonic fibroblasts
Emad K. Ahmed et al.
AGING CELL (2010)
p53, ROS and senescence in the control of aging
Arnaud Vigneron et al.
AGING-US (2010)
The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression
Jean -Philippe Coppe et al.
ANNUAL REVIEW OF PATHOLOGY-MECHANISMS OF DISEASE (2010)
Epigenetic Attenuation of Mitochondrial Superoxide Dismutase 2 in Pulmonary Arterial Hypertension A Basis for Excessive Cell Proliferation and a New Therapeutic Target
Stephen L. Archer et al.
CIRCULATION (2010)
Downregulation of catalase by reactive oxygen species via hypermethylation of CpG island II on the catalase promoter
Ji Young Min et al.
FEBS LETTERS (2010)
Oxidative stress, inflammation, and cancer How are they linked?
Simone Reuter et al.
FREE RADICAL BIOLOGY AND MEDICINE (2010)
Redox regulation of Wnt signalling via nucleoredoxin
Yosuke Funato et al.
FREE RADICAL RESEARCH (2010)
Confining euchromatin/heterochromatin territory: jumonji crosses the line
Hisashi Tamaru
GENES & DEVELOPMENT (2010)
Exposure to Hydrogen Peroxide Induces Oxidation and Activation of AMP-activated Protein Kinase
Jaroslaw W. Zmijewski et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Feedback between p21 and reactive oxygen production is necessary for cell senescence
Joao F. Passos et al.
MOLECULAR SYSTEMS BIOLOGY (2010)
JARID2 regulates binding of the Polycomb repressive complex 2 to target genes in ES cells
Diego Pasini et al.
NATURE (2010)
Oxidative Stress and Oxidative Damage in Carcinogenesis
James E. Klaunig et al.
TOXICOLOGIC PATHOLOGY (2010)
Oxidative stress: A cause and therapeutic target of diabetic complications
Eiichi Araki et al.
JOURNAL OF DIABETES INVESTIGATION (2010)
SENESCENCE Senescence in tumours: evidence from mice and humans
Manuel Collado et al.
NATURE REVIEWS CANCER (2010)
MicroRNAs: Target Recognition and Regulatory Functions
David P. Bartel
CELL (2009)
Foxo1 Links Hyperglycemia to LDL Oxidation and Endothelial Nitric Oxide Synthase Dysfunction in Vascular Endothelial Cells
Jun Tanaka et al.
DIABETES (2009)
Epigenetics, oxidative stress, and Alzheimer disease
Nasser H. Zawia et al.
FREE RADICAL BIOLOGY AND MEDICINE (2009)
Histone demethylase JMJD3 contributes to epigenetic control of INK4a/ARF by oncogenic RAS
Marta Barradas et al.
GENES & DEVELOPMENT (2009)
The H3K27me3 demethylase JMJD3 contributes to the activation of the INK4A-ARF locus in response to oncogene- and stress-induced senescence
Karl Agger et al.
GENES & DEVELOPMENT (2009)
Mice Deficient in Both Mn Superoxide Dismutase and Glutathione Peroxidase-1 Have Increased Oxidative Damage and a Greater Incidence of Pathology but No Reduction in Longevity
Yiqiang Zhang et al.
JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES (2009)
Simultaneous analysis of reactive oxygen species and reduced glutathione content in living cells by polychromatic flow cytometry
Andrea Cossarizza et al.
NATURE PROTOCOLS (2009)
Cellular responses to reactive oxygen species-induced DNA damage and aging
Catharina Bertram et al.
BIOLOGICAL CHEMISTRY (2008)
Redox mechanisms switch on hypoxia-dependent epithelial-mesenchymal transition in cancer cells
Stefania Cannito et al.
CARCINOGENESIS (2008)
Thiol chemistry and specificity in redox signaling
Christine C. Winterbourn et al.
FREE RADICAL BIOLOGY AND MEDICINE (2008)
ROS and p53: A versatile partnership
Bin Liu et al.
FREE RADICAL BIOLOGY AND MEDICINE (2008)
Erasing the methyl mark: histone demethylases at the center of cellular differentiation and disease
Paul A. C. Cloos et al.
GENES & DEVELOPMENT (2008)
From anchorage dependent proliferation to survival: Lessons from redox signalling
Paola Chiarugi
IUBMB LIFE (2008)
Epithelial injury induces an innate repair mechanism linked to cellular senescence and fibrosis involving IGF-binding protein-5
Gordon J. Allan et al.
JOURNAL OF ENDOCRINOLOGY (2008)
Cellular senescence and organismal aging
Jessie C. Jeyapalan et al.
MECHANISMS OF AGEING AND DEVELOPMENT (2008)
Ageing, oxidative stress and cancer: paradigms in parallax
Christopher C. Benz et al.
NATURE REVIEWS CANCER (2008)
The signaling mechanism of ROS in tumor progression
Wen-Sheng Wu
CANCER AND METASTASIS REVIEWS (2006)
Alveolar cell senescence in patients with pulmonary emphysema
Takao Tsuji et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2006)
Cellular senescence in naevi and immortalisation in melanoma: a role for p16?
V. C. Gray-Schopfer et al.
BRITISH JOURNAL OF CANCER (2006)
Apoptosis and aging:: Role of p66Shc Redox protein
Enrica Migliaccio et al.
ANTIOXIDANTS & REDOX SIGNALING (2006)
JmjC-domain-containing proteins and histone demethylation
Robert J. Klose et al.
NATURE REVIEWS GENETICS (2006)
Reactive oxygen species in the control of hypoxia-inducible factor-mediated gene expression
T Kietzmann et al.
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2005)
Escape from therapy-induced accelerated cellular senescence in p53-null lung cancer cells and in human lung cancers
RS Roberson et al.
CANCER RESEARCH (2005)
The cellular level of telomere dysfunction determines induction of senescence or apoptosis in vivo
A Lechel et al.
EMBO REPORTS (2005)
Mitochondrial hTERT exacerbates free-radical-mediated mtDNA damage
JH Santos et al.
AGING CELL (2004)
Interleukin-8 expression is increased in senescent prostatic epithelial cells and promotes the development of benign prostatic hyperplasia
P Castro et al.
PROSTATE (2004)
Role of histone H3 lysine 27 methylation in polycomb-group silencing
R Cao et al.
SCIENCE (2002)
Replicative senescence in normal liver, chronic hepatitis C, and hepatocellular carcinomas
V Paradis et al.
HUMAN PATHOLOGY (2001)
Role of redox-regulated transcription factors in inflammation, aging and age-related diseases
Y Lavrovsky et al.
EXPERIMENTAL GERONTOLOGY (2000)
Identification of Renox, an NAD(P)H oxidase in kidney
M Geiszt et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Expression of senescence-associate beta-galactosidase in enlarged prostates from men with benign prostatic hyperplasia
J Choi et al.
UROLOGY (2000)
Expression of p57(KIP2) potently blocks the growth of human astrocytomas and induces cell senescence
A Tsugu et al.
AMERICAN JOURNAL OF PATHOLOGY (2000)