4.3 Review

Overview of Alzheimer's Disease and Some Therapeutic Approaches Targeting A beta by Using Several Synthetic and Herbal Compounds

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HINDAWI LTD
DOI: 10.1155/2016/7361613

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  1. Indian Council of Medical Research as UGC-RET
  2. Banaras Hindu University as SRF Fellowship
  3. Semmes Foundation
  4. National Institute on Minority Health and Health Disparities from the National Institutes of Health [G12MD007591]
  5. National Institute on Minority Health and Health Disparities [G12MD007591] Funding Source: NIH RePORTER

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Alzheimer's disease (AD) is a complex age-related neurodegenerative disease. In this review, we carefully detail amyloid-beta metabolism and its role in AD. We also consider the various genetic animal models used to evaluate therapeutics. Finally, we consider the role of synthetic and plant-based compounds in therapeutics.

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