期刊
CHEMISTRY-A EUROPEAN JOURNAL
卷 22, 期 1, 页码 97-100出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.201503748
关键词
carbonic anhydrases; drug design; inhibitors; theoretical calculations; X-ray structures
资金
- CNR-DSB Progetto Bandiera InterOmics
Carboxylates are the least investigated class of inhibitors of carbonic anhydrases (CAs). Here we explain the versatility of binding of these molecules to CAs by examining a new adduct of hCA II with N-carboxymethylsaccharin.
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