期刊
ORGANIC LETTERS
卷 18, 期 4, 页码 740-743出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.5b03708
关键词
-
资金
- National Institutes of Health [R01GM069990]
We report here a novel method for the modular synthesis of highly substituted piperazines and related bis-nitrogen heterocycles via a palladium-catalyzed cyclization reaction. The process couples two of the carbons of a propargyl unit with various diamine components to provide nitrogen heterocycles in generly good to excellent yields and high regio- and stereochemical control.
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