α-Carbamoylsulfides as N-Carbamoylimine Precursors in the Visible Light Photoredox-Catalyzed Synthesis of α,α-Disubstituted Amines

A general and practical photoredox-promoted addition of nucleophiles to N-acylimines generated in situ from alpha-amidosulfides using Ru(bpy)(3)(PF6)(2) as the photocatalyst is reported. The broad scope of the reaction toward various nucleophiles and amidosulfide derivatives was explored. This novel protocol provides a rapid, mild, and efficient access to valuable alpha,alpha-disubstituted amines in respectable yields.