CBr4 Mediated Oxidative C-N Bond Formation: Applied in the Synthesis of Imidazo[1,2-α]pyridines and Imidazo[1,2-α]pyrimidines

The carbon tetrabromide mediated oxidative carbon nitrogen bond formation of 2-aminopyridines or 2-aminopyrimidines with beta-keto esters or 1,3-diones, leading to a variety of complex imidazo[1,2-alpha]pyridines or imidazo[1,2-alpha]pyrimidines, is reported. The reactions were realized under mild and metal-free conditions.