Metal-Free Visible-Light-Mediated Oxidative Cross-Coupling of Thiols with P(O)H Compounds Using Air as the Oxidant

Visible light along with 5 mol % of rose bengal, catalyzes the direct S-P(O) coupling between thiols and P(O) H compounds in the presence of air as the green oxidant. The, protocol is operationally simple and amenable to gram-scale synthesis. A variety of S-P(O) coupling products can be readily. prepared in moderate to excellent yields. The reaction features good functional-group tolerance, operational simplicity, and excellent practicality.