期刊
ORGANIC LETTERS
卷 18, 期 6, 页码 1334-1337出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.6b00277
关键词
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资金
- National Nature Science Foundation of China [21272003, 21302169]
- Science Foundation of Zhejiang Sci-Tech University [15062092-Y, 13062121-Y]
- Zhejiang Provincial Top Key Academic Discipline of Chemical Engineering and Technology of Zhejiang Sci-Tech University
A general and expeditious approach for the metal-free mediated synthesis of 1,3,5-trisubstituted 1,2,4-triazoles from hydrazones and aliphatic amines has been achieved under aerobic oxidative conditions. The reaction proceeds through a cascade C-H functionalization, double C-N bonds formation, and oxidative aromatization sequence.
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