期刊
ORGANIC LETTERS
卷 18, 期 19, 页码 4904-4907出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.6b02383
关键词
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Two-step methodology described herein showcases the first example of an oxidation/oxidative amidation cyclization cascade of MCR products toward diverse N-functionalized isatins. Products of both the Ugi 3CR and the Ugi azide reactions are oxidatively cyclized through a postcondensation process utilizing selenium dioxide. This methodology was found to be applicable for the generation of bispeptidomimetic-like isatins containing multiple points of diversification.
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