4.8 Article

Bu4NI-Catalyzed α-Oxyacylation of Carbonyl Compounds with Toluene Derivatives

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ORGANIC LETTERS
卷 18, 期 8, 页码 1916-1919

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AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.6b00749

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资金

  1. National Natural Science Foundation of China [21272148, 21472121, 21272147]
  2. State Key Laboratory of Applied Organic Chemistry
  3. Lanzhou University
  4. Shanghai Key Laboratory of High Temperature Superconductors [14DZ2260700]

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A TBAI (tetrabutylammonium iodide)-catalyzed direct alpha-oxyacylation of carbonyl compounds from readily available toluene derivatives has been developed. The distinguished features of this metal-free protocol include the employment of simple starting material, a wide carbonyl compound scope, and mild reaction conditions.

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