期刊
ORGANIC LETTERS
卷 18, 期 21, 页码 5640-5643出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.6b02883
关键词
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资金
- Fundamental Research Funds for the Central Universities [30916011102, 30916014103]
- National Natural Science Foundation of China [21476116]
- Natural Science Foundation of Jiangsu [BK20141394]
- Priority Academic Program Development of Jiangsu Higher Education Institutions
- Center for Advanced Materials and Technology in Nanjing University of Science and Technology
- UMB
A 2-fluoro-1,3-dicarbonyl-initiated one-pot Michael addition/[5 + 1] annulation/dehydrofluorinative aromatization reaction sequence is introduced for regioselective synthesis of di-, tri-, tetra-, and pentasubstituted pyridines as well as fused pyridines. This simple and modular synthesis is performed using readily available starting materials and under transition-metal catalyst-free conditions.
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