4.8 Article

Copper/Silver Cocatalyzed Oxidative Coupling of Vinylarenes with ICH2CF3 or ICH2CHF2 Leading to β-CF3/CHF2-Substituted Ketones

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ORGANIC LETTERS
卷 18, 期 8, 页码 1780-1783

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AMER CHEMICAL SOC
DOI: 10.1021/acs.orglett.6b00498

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资金

  1. National Natural Science Foundation of China [21502049, 51573040]
  2. Hunan Provincial Natural Science Foundation of China [13JJ5018, 14JJ7028]
  3. Planned Science and Technology Project of Hunan Province, China [2015WK3003]
  4. Hunan Provincial Innovation Foundation for Postgraduate [CX2015B076]

向作者/读者索取更多资源

A novel copper/silver cocatalyzed oxidative coupling of vinylarenes with ICH2CF3 or ICH2CHF2 through a radical process has been developed. The transformation provides an attractive approach to beta-CF3/CHF2-substituted ketones, with the advantages of easily available starting materials and operational simplicity.

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