期刊
ORGANIC & BIOMOLECULAR CHEMISTRY
卷 14, 期 5, 页码 1531-1535出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c5ob02468d
关键词
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资金
- University of Warwick Institute of Advanced Study
- Royal Society
- University of Warwick's URSS undergraduate summer scholarship scheme
- EPSRC [EP/L027100/1] Funding Source: UKRI
- Engineering and Physical Sciences Research Council [EP/L027100/1] Funding Source: researchfish
Difluoromethyl ketones are an under-studied class of ketones which have great potential as useful building blocks for materials and drug design. Here we report a simple and convenient synthesis of this class of compounds via a one-pot difluorination/fragmentation of 1-trifluoromethyl-1,3-diketones which should now allow the chemistry of difluoromethyl ketones to be fully developed.
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