期刊
CHEMISTRY-A EUROPEAN JOURNAL
卷 21, 期 40, 页码 13919-13924出版社
WILEY-V C H VERLAG GMBH
DOI: 10.1002/chem.201502288
关键词
chiral separation; DFT calculations; dynamic chromatography; helical structures; heterocycles
资金
- European Research Council (ERC) [258740]
Helicenes and heterohelicenes are attractive compounds with great potential in materials sciences to be used in optoelectronics as ligand backbones in enantioselective catalysis and as chiral sensors. The properties of these materials are related to the stereodynamics of these helical chiral compounds. However, little is known about features controlling stereodynamics in helicenes; in particular, for heterohelicenes the position of the heteroatom could be relevant in this respect. Herein the complete stereodynamic characterization of monoaza[5]helicenes is shown by enantioselective dynamic HPLC and DFT calculations. At variance with previous theoretical calculations, 1-aza[5]helicene shows a surprisingly high enantiomerization barrier, which is triggered by specific solvent interactions.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据