期刊
OPHTHALMIC EPIDEMIOLOGY
卷 23, 期 -, 页码 22-31出版社
TAYLOR & FRANCIS INC
DOI: 10.1080/09286586.2016.1235715
关键词
Papua New Guinea; prevalence; trachoma; trachomatous inflammation - follicular; trachomatous trichiasis
资金
- Global Trachoma Mapping Project (GTMP) grant from the United Kingdom's Department for International Development [ARIES: 203145]
- United States Agency for International Development (USAID) through the ENVISION project [AID-OAA-A-11-00048]
- United States Agency for International Development (USAID) through END in Asia [OAA-A-10-00051]
- Pfizer
Purpose: We sought to determine the prevalence of trachomatous inflammation - follicular (TF) in children aged 1-9 years, and trachomatous trichiasis (TT) in those aged 15 years, in suspected trachoma-endemic areas of Papua New Guinea (PNG).Methods: We carried out six population-based prevalence surveys using the protocol developed as part of the Global Trachoma Mapping Project.Results: A total of 19,013 individuals were sampled for inclusion, with 15,641 (82.3%) consenting to participate. Four evaluation units had prevalences of TF in children 10%, above which threshold the World Health Organization (WHO) recommends mass drug administration (MDA) of azithromycin for at least three years; Western Province (South Fly/Daru) 11.2% (95% confidence interval, CI, 6.9-17.0%), Southern Highlands (East) 12.2% (95% CI 9.6-15.0%), Southern Highlands (West) 11.7% (95% CI 8.5-15.3%), and West New Britain 11.4% (95% CI 8.7-13.9%). TF prevalence was 5.0-9.9% in Madang (9.4%, 95% CI 6.1-13.0%) and National Capital District (6.0%. 95% CI 3.2-9.1%) where consideration of a single round of MDA is warranted. Cases of TT were not found outside West New Britain, in which four cases were seen, generating an estimated population-level prevalence of TT in adults of 0.10% (95% CI 0.00-0.40%) for West New Britain, below the WHO elimination threshold of 0.2% of those aged 15 years.Conclusion: Trachoma is a public health issue in PNG. However, other than in West New Britain, there are few data to support the idea that trachoma is a cause of blindness in PNG. Further research is needed to understand the stimulus for the active trachoma phenotype in these populations.
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