相关参考文献
注意:仅列出部分参考文献,下载原文获取全部文献信息。Metabolic changes associated with tumor metastasis, part 1: tumor pH, glycolysis and the pentose phosphate pathway
Valery L. Payen et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2016)
Hypoxia-Inducible Factor-2α Limits Natural Killer T Cell Cytotoxicity in Renal Ischemia/Reperfusion Injury
Jianjun Zhang et al.
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2016)
Hypoxia: a key player in antitumor immune response. A Review in the Theme: Cellular Responses to Hypoxia
Muhammad Zaeem Noman et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2015)
Anti-programmed cell death protein-1/ligand-1 therapy in different cancers
B. Homet Moreno et al.
BRITISH JOURNAL OF CANCER (2015)
E3 Ubiquitin Ligase VHL Regulates Hypoxia-Inducible Factor-1α to Maintain Regulatory T Cell Stability and Suppressive Capacity
Jee H. Lee et al.
IMMUNITY (2015)
Effects of extracellular pH and hypoxia on the function and development of antigen-specific cytotoxic T lymphocytes
Yohko Nakagawa et al.
IMMUNOLOGY LETTERS (2015)
The Selective Degradation of Synaptic Connexin 43 Protein by Hypoxia-induced Autophagy Impairs Natural Killer Cell-mediated Tumor Cell Killing
Andres Tittarelli et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Hypoxia impairs anti-viral activity of natural killer (NK) cells but has little effect on anti-fibrotic NK cell functions in hepatitis C virus infection
Franziska Wolter et al.
JOURNAL OF HEPATOLOGY (2015)
Combined Nivolumab and Ipilimumab or Monotherapy in Untreated Melanoma
J. Larkin et al.
NEW ENGLAND JOURNAL OF MEDICINE (2015)
Neoantigens in cancer immunotherapy
Ton N. Schumacher et al.
SCIENCE (2015)
Immunological mechanisms of the antitumor effects of supplemental oxygenation
Stephen M. Hatfield et al.
SCIENCE TRANSLATIONAL MEDICINE (2015)
HIF2a inhibitors for the treatment of VHL disease
Ana Martins Metelo et al.
ONCOTARGET (2015)
Carving out its niche: A role for carbonic anhydrase IX in pre-metastatic niche development
Shawn C. Chafe et al.
ONCOIMMUNOLOGY (2015)
HIF-2α/ITPR1 axis: A new saboteur of NK-mediated lysis
Yosra Messai et al.
ONCOIMMUNOLOGY (2015)
Autophagic degradation of GZMB/granzyme B
Elodie Viry et al.
AUTOPHAGY (2014)
A Mechanism of Hypoxia-Mediated Escape from Adaptive Immunity in Cancer Cells
Ivraym B. Barsoum et al.
CANCER RESEARCH (2014)
ITPR1 Protects Renal Cancer Cells against Natural Killer Cells by Inducing Autophagy
Yosra Messai et al.
CANCER RESEARCH (2014)
PD-L1 is a novel direct target of HIF-1α., and its blockade under hypoxia enhanced MDSC-mediated T cell activation
Muhammad Zaeem Noman et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2014)
Ipilimumab versus placebo after radiotherapy in patients with metastatic castration-resistant prostate cancer that had progressed after docetaxel chemotherapy (CA184-043): a multicentre, randomised, double-blind, phase 3 trial
Eugene D. Kwon et al.
LANCET ONCOLOGY (2014)
Tumor endothelium FasL establishes a selective immune barrier promoting tolerance in tumors
Gregory T. Motz et al.
NATURE MEDICINE (2014)
O2.04 * TREATMENT WITH OMX-4.80, A TUMOR-PENETRATING TUNABLE OXYGEN CARRIER, REDUCES TUMOR HYPOXIA AND DRAMATICALLY ENHANCES RADIATION THERAPY IN INTRACRANIAL MODELS OF GLIOBLASTOMA
A. Krtolica et al.
NEURO-ONCOLOGY (2014)
Targeting hypoxia at the forefront of anticancer immune responses
Muhammad Zaeem Noman et al.
ONCOIMMUNOLOGY (2014)
Impeding Macrophage Entry into Hypoxic Tumor Areas by Sema3A/Nrp1 Signaling Blockade Inhibits Angiogenesis and Restores Antitumor Immunity
Andrea Casazza et al.
CANCER CELL (2013)
Immune-suppressive properties of the tumor microenvironment
Juergen C. Becker et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2013)
Cutting Edge: Hypoxia-Induced Nanog Favors the Intratumoral Infiltration of Regulatory T Cells and Macrophages via Direct Regulation of TGF- β1
Meriem Hasmim et al.
JOURNAL OF IMMUNOLOGY (2013)
Hypoxia Contributes to Melanoma Heterogeneity by Triggering HIF1α-Dependent Phenotype Switching
Daniel S. Widmer et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2013)
Hypoxia-inducible factors enhance the effector responses of CD8+ T cells to persistent antigen
Andrew L. Doedens et al.
NATURE IMMUNOLOGY (2013)
Microenvironmental regulation of tumor progression and metastasis
Daniela F. Quail et al.
NATURE MEDICINE (2013)
Hypoxia Induced Impairment of NK Cell Cytotoxicity against Multiple Myeloma Can Be Overcome by IL-2 Activation of the NK Cells
Subhashis Sarkar et al.
PLOS ONE (2013)
Granzyme B degradation by autophagy decreases tumor cell susceptibility to natural killer-mediated lysis under hypoxia
Joanna Baginska et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Hypoxia-driven immunosuppression contributes to the pre-metastatic niche
Jaclyn Sceneay et al.
ONCOIMMUNOLOGY (2013)
Ways to enhance lymphocyte trafficking into tumors and fitness of tumor infiltrating lymphocytes
Matteo Bellone et al.
FRONTIERS IN ONCOLOGY (2013)
The tumor microenvironment and strategies to improve drug distribution
Jasdeep K. Saggar et al.
FRONTIERS IN ONCOLOGY (2013)
Clinical outcome of patients with various advanced cancer types vaccinated with an optimized cryptic human telomerase reverse transcriptase (TERT) peptide: results of an expanded phase II study
A. Kotsakis et al.
ANNALS OF ONCOLOGY (2012)
Hypoxia-induced autophagy A new player in cancer immunotherapy?
Muhammad Zaeem Noman et al.
AUTOPHAGY (2012)
Primary Tumor Hypoxia Recruits CD11b+/Ly6Cmed/Ly6G+ Immune Suppressor Cells and Compromises NK Cell Cytotoxicity in the Premetastatic Niche
Jaclyn Sceneay et al.
CANCER RESEARCH (2012)
Hypoxia-Inducible miR-210 Regulates the Susceptibility of Tumor Cells to Lysis by Cytotoxic T Cells
Muhammad Zaeem Noman et al.
CANCER RESEARCH (2012)
Chemokine C-C motif receptor 5 and C-C motif ligand 5 promote cancer cell migration under hypoxia
Sensen Lin et al.
CANCER SCIENCE (2012)
Hypoxia-Inducible Factors in Physiology and Medicine
Gregg L. Semenza
CELL (2012)
Immunology in the clinic review series; focus on cancer: tumour-associated macrophages: undisputed stars of the inflammatory tumour microenvironment
P. Allavena et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2012)
Recent advances in hypoxia-inducible factor (HIF)-1 inhibitors
Yan Xia et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2012)
PDK1 regulation of mTOR and hypoxia-inducible factor 1 integrate metabolism and migration of CD8+ T cells
David K. Finlay et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2012)
Hypoxia-inducible factor-1 alpha-dependent induction of FoxP3 drives regulatory T-cell abundance and function during inflammatory hypoxia of the mucosa
Eric T. Clambey et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Hypoxia-inducible factors: mediators of cancer progression and targets for cancer therapy
Gregg L. Semenza
TRENDS IN PHARMACOLOGICAL SCIENCES (2012)
The HIF-1α Hypoxia Response in Tumor-Infiltrating T Lymphocytes Induces Functional CD137 (4-1BB) for Immunotherapy
Asis Palazon et al.
CANCER DISCOVERY (2012)
Blocking Hypoxia-Induced Autophagy in Tumors Restores Cytotoxic T-Cell Activity and Promotes Regression
Muhammad Zaeem Noman et al.
CANCER RESEARCH (2011)
PGE2-Induced CXCL12 Production and CXCR4 Expression Controls the Accumulation of Human MDSCs in Ovarian Cancer Environment
Natasa Obermajer et al.
CANCER RESEARCH (2011)
Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
Eric V. Dang et al.
CELL (2011)
HIF1α-dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells
Lewis Z. Shi et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2011)
Chemokine nitration prevents intratumoral infiltration of antigen-specific T cells
Barbara Molon et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2011)
IL-17+ Regulatory T Cells in the Microenvironments of Chronic Inflammation and Cancer
Ilona Kryczek et al.
JOURNAL OF IMMUNOLOGY (2011)
Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and Treg cells
Andrea Facciabene et al.
NATURE (2011)
Hypoxia and lineage specification of cell line-derived colorectal cancer stem cells
Trevor M. Yeung et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
In vivo T cell activation in lymphoid tissues is inhibited in the oxygen-poor microenvironment
Akio Ohta et al.
FRONTIERS IN IMMUNOLOGY (2011)
Targeting hypoxia in cancer therapy
William R. Wilson et al.
NATURE REVIEWS CANCER (2011)
Microenvironmental Hypoxia Orchestrating the Cell Stroma Cross Talk, Tumor Progression and Antitumor Response
Muhammad Zaeem Noman et al.
CRITICAL REVIEWS IN IMMUNOLOGY (2011)
Impact of the hypoxic tumor microenvironment on the regulation of cancer stem cell characteristics
Qun Lin et al.
CANCER BIOLOGY & THERAPY (2010)
Macrophage Expression of Hypoxia-Inducible Factor-1α Suppresses T-Cell Function and Promotes Tumor Progression
Andrew L. Doedens et al.
CANCER RESEARCH (2010)
Different Tumor Microenvironments Contain Functionally Distinct Subsets of Macrophages Derived from Ly6C(high) Monocytes
Kiavash Movahedi et al.
CANCER RESEARCH (2010)
HIF-1α regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment
Cesar A. Corzo et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2010)
Phase 2 Trial of Single Agent Ipilimumab (Anti-CTLA-4) for Locally Advanced or Metastatic Pancreatic Adenocarcinoma
Richard E. Royal et al.
JOURNAL OF IMMUNOTHERAPY (2010)
PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors
Michael A. Curran et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Immune surveillance of human cancer: if the cytotoxic T-lymphocytes play the music, does the tumoral system call the tune?
A. Hamai et al.
TISSUE ANTIGENS (2010)
HIF-1 Inhibitors for Cancer Therapy: From Gene Expression to Drug Discovery
G. L. Semenza
CURRENT PHARMACEUTICAL DESIGN (2009)
Damage control by hypoxia-inhibited AK
Michail V. Sitkovsky
BLOOD (2008)
HIF1α induces the recruitment of bone marrow-derived vascular modulatory cells to regulate tumor angiogenesis and invasion
Rose Du et al.
CANCER CELL (2008)
Hypoxia controls CD4+CD25+ regulatory T-cell homeostasis via hypoxia-inducible factor-1α
Jeremy Ben-Shoshan et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2008)
Macrophage activation and polarization
Fernando Oneissi Martinez et al.
FRONTIERS IN BIOSCIENCE-LANDMARK (2008)
Targeted Deletion of HIF-1α Gene in T Cells Prevents their Inhibition in Hypoxic Inflamed Tissues and Improves Septic Mice Survival
Manfred Thiel et al.
PLOS ONE (2007)
Altered recognition of antigen is a mechanism of CD8+ T cell tolerance in cancer
Srinivas Nagaraj et al.
NATURE MEDICINE (2007)
Adenosine generation catalyzed by CD39 and CD73 expressed on regulatory T cells mediates immune suppression
Silvia Deaglio et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2007)
Hypoxia-dependent anti-inflammatory pathways in protection of cancerous tissues
D. Lukashev et al.
CANCER AND METASTASIS REVIEWS (2007)
Inhibitory effect of tumor cell-derived lactic acid on human T cells
Karin Fischer et al.
BLOOD (2007)
Involvement of cyclooxygenase-2-prostaglandin E2 pathway in interleukin-8 production in gastric cancer cells
Hisashi Takehara et al.
DIGESTIVE DISEASES AND SCIENCES (2006)
T regulatory and primed uncommitted CD4 T cells express CD73, which suppresses effector CD4 T cells by converting 5′-adenosine monophosphate to adenosine
James J. Kobie et al.
JOURNAL OF IMMUNOLOGY (2006)
Cutting edge:: Hypoxia-inducible factor 1α and its activation-inducible short isoform I.1 negatively regulate functions of CD4+ and CD8+ T lymphocytes
Dmitriy Lukashev et al.
JOURNAL OF IMMUNOLOGY (2006)
Cannibalism of live lymphocytes by human metastatic but not primary melanoma cells
L Lugini et al.
CANCER RESEARCH (2006)
TCR engagement increases hypoxia-inducible factor-1α protein synthesis via rapamycin-sensitive pathway under hypoxic conditions in human peripheral T cells
H Nakamura et al.
JOURNAL OF IMMUNOLOGY (2005)
Oxygenation inhibits the physiological tissue-protecting mechanism and thereby exacerbates acute inflammatory lung injury
M Thiel et al.
PLOS BIOLOGY (2005)
Hypoxia modulates early events in T cell receptor-mediated activation in human T lymphocytes via Kv1.3 channels
JR Robbins et al.
JOURNAL OF PHYSIOLOGY-LONDON (2005)
Hypoxia-induced gene expression in human macrophages - Implications for ischemic tissues and hypoxia-regulated gene therapy
B Burke et al.
AMERICAN JOURNAL OF PATHOLOGY (2003)
HER-2/neu and hTERT cryptic epitopes as novel targets for broad spectrum tumor immunotherapy
A Scardino et al.
JOURNAL OF IMMUNOLOGY (2002)
Differential regulation of two alternatively spliced isoforms of hypoxia-inducible factor-1α in activated T lymphocytes
D Lukashev et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Differential effects of physiologically relevant hypoxic conditions on T lymphocyte development and effector functions
CC Caldwell et al.
JOURNAL OF IMMUNOLOGY (2001)
Matrilysin [MMP-7] expression selects for cells with reduced sensitivity to apoptosis
B Fingleton et al.
NEOPLASIA (2001)