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Zhu Shen et al.
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Chia-Hsin Chan et al.
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Junxia Min et al.
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Emerging role of Lys-63 ubiquitination in protein kinase and phosphatase activation and cancer development
W-L Yang et al.
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Phosphorylation-dependent regulation of cytosolic localization and oncogenic function of Skp2 by Akt/PKB
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K. V. Bhatt et al.
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Crucial role of p53-dependent cellular senescence in suppression of Pten-deficient tumorigenesis
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Down-regulation of human DAB2IP gene expression mediated by polycomb Ezh2 complex and histone deacetylase in prostate cancer
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Clinicopathological significance of EZH2 mRNA expression in patients with hepatocellular carcinoma
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