期刊
OCULAR SURFACE
卷 14, 期 4, 页码 419-434出版社
ELSEVIER
DOI: 10.1016/j.jtos.2016.06.003
关键词
corneal conjunctivalization; contact lens; limbal stem cell deficiency; limbal stem cells
资金
- National Institute of Health [R01 EY024349-01A1, EY01792]
- Research to Prevent Blindness
Limbal stem cell deficiency (LSCD) is a pathologic condition caused by the dysfunction and/or destruction of stem cell precursors of the corneal epithelium, typified clinically by corneal conjunctivalization. The purpose of this review is to critically discuss a less well-known cause of limbal stem cell disease: contact lens (CL) wear. A literature search was conducted to include original articles containing patients with CL-induced LSCD. This review describes epidemiology, diagnostic strategies, pathogenesis, differential diagnosis, and treatment modalities for this condition.
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