期刊
OCEANOLOGICAL AND HYDROBIOLOGICAL STUDIES
卷 45, 期 4, 页码 605-614出版社
WALTER DE GRUYTER GMBH
DOI: 10.1515/ohs-2016-0050
关键词
pharmaceutical residues; pharmaceutical bioaccumulation; Mytilus sp.; 17 alpha-ethynylestradiol (EE2); non-steroidal anti-inflammatory drugs (NSAIDs)
Pharmaceuticals are commonly found in water collected from wastewater treatment plants, fresh water and saline water. Their presence in water may result in constant accumulation in living organisms, and consequently a negative impact on those organisms. Abiotic samples collected from the Gulf of Gdansk were already proven to be polluted by several classes of pharmaceuticals, but the bioaccumulation was not investigated as far. This study presents the first results on the accumulation of pharmaceuticals in Mytilus edulis trossulus (Gould 1890) mussels collected from the Gulf of Gdansk. The content of target 6 non-steroidal anti-inflammatory pharmaceuticals (ibuprofen, flurbiprofen, diclofenac, paracetamol, naproxen, ketoprofen) and 17 alpha-ethynylestradiol in water and tissue samples was determined. The selected pharmaceuticals (paracetamol, flurbiprofen, 17 alpha-ethynylestradiol) were found only in the largest individuals. The in situ BAFs calculated for paracetamol and flurbiprofen were 2850 and 16154 l kg(-1) (dry weight), respectively, suggesting a high potential for the bioaccumulation of these compounds. The synthetic hormone 17 alpha-ethynylestradiol was also found in the collected mussels at the concentration of 310 ng g(-1) of dry weight. Generally, the examined mussels showed poor condition and it is highly likely that the accumulated pharmaceuticals are one of the important factors contributing to this.
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