期刊
OBESITY
卷 24, 期 2, 页码 424-429出版社
WILEY
DOI: 10.1002/oby.21343
关键词
-
资金
- Erasmus MC
- University Medical Center, Rotterdam
- Erasmus University Rotterdam
- Netherlands Organization for Health Research and Development (ZonMw)
- Netherlands Organization for Scientific Research (NWO)
- Ministry of Health, Welfare and Sport
- Ministry of Youth and Families
- European Union [289346]
- Portuguese Foundation for Science and Technology [SFRH/BD/81123/2011]
- Netherlands Organization for Health Research and Development [VIDI 016.136.361]
- European Research Council [ERC-2014-CoG-648916]
- Fundação para a Ciência e a Tecnologia [SFRH/BD/81123/2011] Funding Source: FCT
ObjectiveTo examine the associations of infant subcutaneous fat with cardiovascular risk factors at school-age. MethodsIn a population-based prospective cohort study among 808 children, total subcutaneous fat (sum of biceps, triceps, suprailiacal, and subscapular skinfold thicknesses) and central-to-total subcutaneous fat ratio (sum of suprailiacal and subscapular skinfold thicknesses/total subcutaneous fat) at 1.5 and 24 months were estimated. At 6 years, body mass index, blood pressure, cholesterol, triglycerides, and insulin levels were measured. ResultsInfant subcutaneous fat measures were not associated with childhood blood pressure, triglycerides, or insulin levels. A 1-standard-deviation score (SDS) higher total subcutaneous fat at 1.5 months was, independently of body mass index, associated with lower low-density lipoprotein (LDL)-cholesterol levels at 6 years. In contrast, a 1-SDS higher total subcutaneous fat at 24 months was associated with higher total-cholesterol [difference 0.13 (95% confidence interval (CI) 0.03, 0.23) SDS] and LDL-cholesterol levels [difference 0.12 (95% CI 0.02, 0.21) SDS] at 6 years. There were no associations of central-to-total subcutaneous fat ratio with childhood cholesterol levels. ConclusionsThese results suggest that infant total subcutaneous fat is weakly associated with cholesterol levels at school-age. Further studies are needed to assess the long-term cardiometabolic consequences of infant body fat.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据