Ni(H)-Catalyzed Sulfonylation of ortho C-H Bonds in Aromatic Amides Utilizing an N,N-Bidentate Directing Group

The reaction of aromatic amides containing a 5-chloro-8-aminoquinoline moiety as the directing group with arylsulfonyl chlorides in the presence of Ni(OTf)(2) as the catalyst results in sulfonylation at the ortho-position. Various arylsulfonyl chlorides can be used as the coupling partners.