期刊
NUCLEIC ACIDS RESEARCH
卷 44, 期 W1, 页码 W474-W478出版社
OXFORD UNIV PRESS
DOI: 10.1093/nar/gkw361
关键词
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资金
- Engineering and Physical Research council [EP/K503769/1, EP/G037280/1]
- Engineering and Physical Sciences Research Council [1367757, 1231608] Funding Source: researchfish
SAbPred is a server that makes predictions of the properties of antibodies focusing on their structures. Antibody informatics tools can help improve our understanding of immune responses to disease and aid in the design and engineering of therapeutic molecules. SAbPred is a single platform containing multiple applications which can: number and align sequences; automatically generate antibody variable fragment homology models; annotate such models with estimated accuracy alongside sequence and structural properties including potential developability issues; predict paratope residues; and predict epitope patches on protein antigens. The server is available at http://opig.stats.ox.ac.uk/webapps/sabpred.
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